SCHEMBL13420987

SCHEMBL13420987

Nc1ccc(CCNc2nc(Nc3ccccc3)nc(Nc3ccc(CCNc4nc(NCCO)nc(Nc5ccccc5)n4)cc3)n2)cc1

nearest known ligand 0.82

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
FCGR3B O75015 1/20 0.82
FCGR1A P12314 1/20 0.82
FCGR2A P12318 1/20 0.82
RECQL P46063 1/20 0.69
MCL1 Q07820 1/20 0.69
KCNH3 Q9ULD8 10/20 0.62
TDP1 Q9NUW8 1/20 0.57
GBA1 P04062 1/20 0.54
KMT2A Q03164 1/20 0.51
MAPT P10636 1/20 0.48
CDK5 Q00535 1/20 0.48
CDK5R1 Q15078 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3200004 0.99 FCGR3B (0.80) FCGR3BFCGR1AFCGR2ARECQLMCL1
SCHEMBL13421296 0.93 FCGR3B (0.96) FCGR3BFCGR1AFCGR2ARECQLMCL1
SCHEMBL13917176 0.90 FCGR3B (1.00) FCGR3BFCGR1AFCGR2ARECQLMCL1
SCHEMBL13421038 0.90 FCGR3B (0.78) FCGR3BFCGR1AFCGR2ARECQLMCL1
SCHEMBL13421034 0.89 GBA1 (0.70) FCGR3BFCGR1AFCGR2ARECQLMCL1
SCHEMBL13420997 0.88 RECQL (0.71) FCGR3BFCGR1AFCGR2ARECQLMCL1
SCHEMBL13421032 0.87 FCGR3B (0.71) FCGR3BFCGR1AFCGR2ARECQLMCL1
SCHEMBL3203902 0.87 RECQL (0.69) FCGR3BFCGR1AFCGR2ARECQLMCL1
Benzene SCHEMBL3952455 0.85 FCGR3B (0.65) FCGR3BFCGR1AFCGR2ARECQLMCL1
SCHEMBL13917185 0.84 FCGR3B (0.89) FCGR3BFCGR1AFCGR2ARECQLMCL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1687297-B1 TRIAZINE DIMERS FOR THE TREATMENT OF AUTOIMMUNE DISEASES PROMETIC BIOSCIENCES INC (CA) 2014-06-18 EP disclosed
US-7683061-B2 Triazine dimers for the treatment of autoimmune diseases PROMETIC BIOSCIENCES INC. (CA) 2010-03-23 US disclosed
US-7683061-B2 Triazine dimers for the treatment of autoimmune diseases PROMETIC BIOSCIENCES INC. (CA) 2010-03-23 US disclosed
US-20070149528-A1 Triazine dimers for the treatment of autoimmune diseases PROMETIC PHARMA SMT LIMITED (GB) 2007-06-28 US disclosed
US-20070149528-A1 Triazine dimers for the treatment of autoimmune diseases PROMETIC PHARMA SMT LIMITED (GB) 2007-06-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070149528-A1 Triazine dimers for the treatment of autoimmune diseases SSB, TLR5, ICOS FCGR3B 19/4885FCGR1A 18/4885FCGR2A 4/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.