SCHEMBL13917185

SCHEMBL13917185

Nc1cccc(CCNc2nc(Nc3ccc(CCNc4nc(NCCO)nc(Nc5cccc(N)c5)n4)cc3)nc(Nc3cccc(N)c3)n2)c1

nearest known ligand 0.89

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FCGR3B O75015 1/20 0.89
FCGR1A P12314 1/20 0.89
FCGR2A P12318 1/20 0.89
RECQL P46063 1/20 0.54
MCL1 Q07820 1/20 0.54
KCNH3 Q9ULD8 6/20 0.50
TDP1 Q9NUW8 1/20 0.46
GBA1 P04062 5/20 0.44
KMT2A Q03164 1/20 0.44
CA12 O43570 2/20 0.43
CA1 P00915 2/20 0.43
CA2 P00918 2/20 0.43
CA5A P35218 2/20 0.43
CA9 Q16790 2/20 0.43
CA14 Q9ULX7 2/20 0.43
CA5B Q9Y2D0 1/20 0.43
CA3 P07451 1/20 0.43
CA4 P22748 1/20 0.43
CA6 P23280 1/20 0.43
CA7 P43166 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13917176 0.94 FCGR3B (1.00) FCGR3BFCGR1AFCGR2ARECQLMCL1
SCHEMBL13421296 0.92 FCGR3B (0.96) FCGR3BFCGR1AFCGR2ARECQLMCL1
SCHEMBL13421092 0.89 FCGR3B (0.81) FCGR3BFCGR1AFCGR2ARECQLMCL1
SCHEMBL13917183 0.88 FCGR3B (0.80) FCGR3BFCGR1AFCGR2ARECQLMCL1
SCHEMBL13917186 0.88 FCGR3B (0.80) FCGR3BFCGR1AFCGR2ARECQLMCL1
SCHEMBL13917188 0.88 FCGR3B (0.80) FCGR3BFCGR1AFCGR2ARECQLMCL1
SCHEMBL13421062 0.88 FCGR3B (0.80) FCGR3BFCGR1AFCGR2ARECQLMCL1
SCHEMBL13921814 0.87 FCGR3B (0.77) FCGR3BFCGR1AFCGR2ARECQLMCL1
SCHEMBL13921798 0.85 FCGR3B (0.84) FCGR3BFCGR1AFCGR2ARECQLMCL1
SCHEMBL13421097 0.85 FCGR3B (0.75) FCGR3BFCGR1AFCGR2ARECQLMCL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090075867-A1 Triazine compounds and compositions thereof for the treatment of cancers PROMETIC BIOSCIENCE INC. (CA) 2009-03-19 US disclosed
US-20090075867-A1 Triazine compounds and compositions thereof for the treatment of cancers PROMETIC BIOSCIENCE INC. (CA) 2009-03-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090075867-A1 Triazine compounds and compositions thereof for the treatment of cancers MCTS1, TYR, BRAF FCGR3B 4723/4885FCGR1A 4810/4885FCGR2A 4674/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.