Benzene

Benzene

SCHEMBL134227

C=C(C)C(=C)C.c1ccccc1

nearest known ligand 0.44

Full drug profile on Sugi Atlas →

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 3/20 0.38
ALDH1A1 P00352 3/20 0.35
KDM4E B2RXH2 1/20 0.35
TP53 P04637 2/20 0.33
TSHR P16473 2/20 0.33
HSD17B10 Q99714 1/20 0.31
HPGD P15428 1/20 0.31
FFAR3 O14843 1/20 0.31
LCK P06239 1/20 0.31
FYN P06241 1/20 0.31
ELANE P08246 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzene SCHEMBL4426066 0.95 TDP1 (0.35) TDP1ALDH1A1KDM4ETP53TSHR
Benzene SCHEMBL6003979 0.95 TDP1 (0.35) TDP1ALDH1A1KDM4ETP53TSHR
Benzene SCHEMBL17504475 0.84 TP53 (0.36) TDP1ALDH1A1KDM4ETP53TSHR
Benzene SCHEMBL1685406 0.84 TP53 (0.36) TDP1ALDH1A1KDM4ETP53TSHR
SCHEMBL23446 0.84
Biphenyl SCHEMBL2343742 0.79 ALDH1A1 (0.56) TDP1ALDH1A1KDM4EHSD17B10
Benzene SCHEMBL17022337 0.79 TAS2R38 (0.33) TDP1ALDH1A1KDM4E
Methacrylic Acid SCHEMBL3426195 0.79 TDP1 (0.47) TDP1ALDH1A1KDM4ETSHRHSD17B10
Methacrylic Acid SCHEMBL225835 0.79 TDP1 (0.47) TDP1ALDH1A1KDM4ETSHRHSD17B10
Methacrylic Acid SCHEMBL3858692 0.79 TDP1 (0.47) TDP1ALDH1A1KDM4ETSHRHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2545 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260132349-A1 DIBLOCK AND TRIBLOCK COPOLYMER CONCENTRATES FOR LUBRICATING OIL COMPOSITIONS INFINEUM INTERNATIONAL LIMITED (US) 2026-05-14 US claimed
WO-2026087378-A1 DIBLOCK AND TRIBLOCK COPOLYMER CONCENTRATES FOR LUBRICATING OIL COMPOSITIONS INFINEUM INTERNATIONAL LIMITED (GB) 2026-04-30 WO claimed
EP-4646450-A1 LINEAR TELECHELIC DIENE COPOLYMERS AND THEIR USE IN TIRE COMPONENTS BRIDGESTONE CORPORATION (JP) 2025-11-12 EP claimed
EP-3651896-B1 SULFUR-DOPED CARBONACEOUS POROUS MATERIALS UNIV LIVERPOOL (GB) 2025-09-03 EP claimed
CN-120037980-A Catalyst for preparing isosorbide, preparation method thereof and method for preparing isosorbide by reacting sorbitol with dimethyl carbonate 中国石油化工股份有限公司 2025-05-27 CN claimed
CN-120040832-A Ion exchange resin for transesterification and preparation method and application thereof 中国石油化工股份有限公司 2025-05-27 CN claimed
CN-120019881-A Catalyst for cycloaddition preparation of cyclic carbonate, preparation method and application thereof 中国石油化工股份有限公司 2025-05-20 CN claimed
CN-120019882-A Macroporous composite ion exchange resin, preparation method, method for preparing glycol by epoxy alkane hydration and application 中国石油化工股份有限公司 2025-05-20 CN claimed
CN-120005074-A Styrene type macroporous resin and preparation method thereof 中国石油化工股份有限公司 2025-05-16 CN claimed
EP-3526306-B1 PHOTOCHROMIC ARTICLE SDC TECH INC (US) 2025-02-26 EP claimed
US-4426495-A Preparation of star polymers THE GENERAL TIRE & RUBBER COMPANY (US) 1984-01-17 US claimed
US-4409368-A DIVINYLBENZENE, DIISOPROPENYLBENZENE, LITHIUM CATALYSTS THE GENERAL TIRE & RUBBER COMPANY (US) 1983-10-11 US claimed
US-4405786-A Addition products of di-acetylene-terminated polyimide derivatives and an dienophile having ethylene groups PLASTICS ENGINEERING COMPANY (US) 1983-09-20 US claimed
EP-0088223-A1 Manufacture of isocyanates AMERICAN CYANAMID COMPANY (US) 1983-09-14 EP claimed
US-4379767-A Manufacture of isocyanates AMERICAN CYANAMID COMPANY (US) 1983-04-12 US claimed
EP-0028394-A1 Control polymerization of addition polymerizable monomers with small amounts of non-conjugated difunctional monomers THE DOW CHEMICAL COMPANY (US) 1981-05-13 EP claimed
US-4039593-A CAPPING ORGANO-DILITHIUM POLYMERS, N,N,N*,N*-TETRAMETHYLENEDIAMINE ON LITHIUM CORPORATION OF AMERICA (US) 1977-08-02 US claimed
US-4001350-A BLOCK AND GRAFT COPOLYMERS BASF AKTIENGESELLSCHAFT (DT) 1977-01-04 US claimed
US-3965039-A Ion-exchange molded catalyst and method of its preparation CHAPLITS DONAT N 1976-06-22 US claimed
US-3954894-A Organotrilithium polymerization initiators LITHIUM CORPORATION OF AMERICA (US) 1976-05-04 US claimed