Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | KIF11 | P52732 | 1/20 | 0.45 |
| ▸ | LTA4H | P09960 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CDK2 | P24941 | 1/20 | 0.41 |
| ▸ | FLT4 | P35916 | 1/20 | 0.41 |
| ▸ | SPR | P35270 | 1/20 | 0.40 |
| ▸ | NAMPT | P43490 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13437370 | 0.81 | RAB9A (0.53) | RAB9ALTA4HNPC1L3MBTL1ALDH1A1 | |
| SCHEMBL3643530 | 0.79 | RAB9A (0.54) | RAB9ALTA4HNPC1ALDH1A1POLB | |
| SCHEMBL22851453 | 0.78 | RAB9A (0.53) | RAB9ALTA4HNPC1L3MBTL1ALDH1A1 | |
| SCHEMBL2128107 | 0.77 | F2 (0.41) | HPGDPOLB | |
| SCHEMBL4762870 | 0.77 | MAPT (0.56) | RAB9AL3MBTL1HPGDALDH1A1HTT | |
| SCHEMBL4507702 | 0.76 | LMNA (0.53) | RAB9ANPC1L3MBTL1ALDH1A1POLB | |
| SCHEMBL19176792 | 0.76 | LMNA (0.63) | L3MBTL1ALDH1A1POLBSMN1; SMN2GAA | |
| SCHEMBL4383419 | 0.76 | RAB9A (0.50) | RAB9ALTA4HNPC1L3MBTL1HPGD | |
| SCHEMBL15055378 | 0.76 | RAB9A (0.50) | RAB9AKIF11LTA4HNPC1L3MBTL1 | |
| SCHEMBL4572901 | 0.76 | RAB9A (0.50) | RAB9ALTA4HNPC1CDK2FLT4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7683097-B2 | Topoisomerase inhibitors | Propharmacon Inc. (US) | 2010-03-23 | — | — | US | disclosed |