Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | PLA2G10 | O15496 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.35 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13483704 | 0.93 | HDAC10 (0.40) | HDAC10HDAC6PLA2G10ALDH1A1TSHR | |
| SCHEMBL13425016 | 0.87 | HDAC10 (0.36) | HDAC10HDAC6ALDH1A1TSHRNOTUM | |
| SCHEMBL13425027 | 0.87 | HDAC10 (0.39) | HDAC10HDAC6ALDH1A1TSHRKMT2A | |
| SCHEMBL6756680 | 0.86 | ALDH1A1 (0.41) | HDAC10HDAC6PLA2G10ALDH1A1TSHR | |
| SCHEMBL13425019 | 0.86 | ALDH1A1 (0.43) | HDAC10HDAC6ALDH1A1TSHRNOTUM | |
| SCHEMBL13425058 | 0.85 | HDAC10 (0.36) | HDAC10HDAC6PLA2G10ALDH1A1TSHR | |
| SCHEMBL15447623 | 0.84 | ALDH1A1 (0.50) | HDAC10HDAC6PLA2G10ALDH1A1TSHR | |
| SCHEMBL13425061 | 0.84 | CYP19A1 (0.39) | HDAC10HDAC6ALDH1A1TSHRKMT2A | |
| SCHEMBL13425020 | 0.84 | KMT2A (0.40) | HDAC10HDAC6PLA2G10ALDH1A1TSHR | |
| SCHEMBL13456060 | 0.83 | HDAC10 (0.40) | HDAC10HDAC6PLA2G10ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2094810-B1 | ORGANIC ELECTROLUMINESCENT DEVICE AND INDOLE DERIVATIVE | UDC IRELAND LTD (IE) | 2017-08-09 | — | — | EP | disclosed |
| US-8337999-B2 | Organic electroluminescent device including at least one layer containing an indole derivative | UDC IRELAND LIMITED (IE) | 2012-12-25 | — | — | US | disclosed |
| US-8337999-B2 | Organic electroluminescent device including at least one layer containing an indole derivative | UDC IRELAND LIMITED (IE) | 2012-12-25 | — | — | US | disclosed |
| US-20100066243-A1 | ORGANIC ELECTROLUMINESCENT DEVICE AND INDOLE DERIVATIVE | FUJIFILM CORPORATION (JP) | 2010-03-18 | — | — | US | disclosed |
| US-20100026174-A1 | ORGANIC ELECTROLUMINESCENT DEVICE | FUJIFILM CORPORATION (JP) | 2010-02-04 | — | — | US | disclosed |
| US-20100026174-A1 | ORGANIC ELECTROLUMINESCENT DEVICE | FUJIFILM CORPORATION (JP) | 2010-02-04 | — | — | US | disclosed |
| WO-2008066195-A1 | ORGANIC ELECTROLUMINESCENT DEVICE AND INDOLE DERIVATIVE | FUJIFILM CORPORATION (JP) | 2008-06-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100066243-A1 | ORGANIC ELECTROLUMINESCENT DEVICE AND INDOLE DERIVATIVE | IDO1, IDO2, L1CAM | HDAC10 1020/4885HDAC6 4335/4885PLA2G10 2082/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.