Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 5/20 | 0.38 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | APP | P05067 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15447623 | 0.94 | ALDH1A1 (0.50) | ALDH1A1TSHRHDAC10HDAC6KDM4E | |
| SCHEMBL13425027 | 0.93 | HDAC10 (0.39) | ALDH1A1TSHRHDAC10HDAC6KDM4E | |
| SCHEMBL13483704 | 0.92 | HDAC10 (0.40) | ALDH1A1TSHRHDAC10HDAC6KDM4E | |
| SCHEMBL6756680 | 0.89 | ALDH1A1 (0.41) | ALDH1A1TSHRHDAC10HDAC6KDM4E | |
| SCHEMBL13425009 | 0.86 | HDAC10 (0.36) | ALDH1A1TSHRHDAC10HDAC6KDM4E | |
| SCHEMBL13425016 | 0.86 | HDAC10 (0.36) | ALDH1A1TSHRHDAC10HDAC6KDM4E | |
| SCHEMBL13425041 | 0.85 | KDM4E (0.36) | ALDH1A1TSHRHDAC10HDAC6KDM4E | |
| SCHEMBL13425058 | 0.84 | HDAC10 (0.36) | ALDH1A1TSHRHDAC10HDAC6KDM4E | |
| SCHEMBL13425028 | 0.84 | TP53 (0.39) | ALDH1A1TSHRHDAC10HDAC6KDM4E | |
| SCHEMBL13425020 | 0.83 | KMT2A (0.40) | ALDH1A1TSHRHDAC10HDAC6KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2094810-B1 | ORGANIC ELECTROLUMINESCENT DEVICE AND INDOLE DERIVATIVE | UDC IRELAND LTD (IE) | 2017-08-09 | — | — | EP | disclosed |
| US-8337999-B2 | Organic electroluminescent device including at least one layer containing an indole derivative | UDC IRELAND LIMITED (IE) | 2012-12-25 | — | — | US | disclosed |
| US-8337999-B2 | Organic electroluminescent device including at least one layer containing an indole derivative | UDC IRELAND LIMITED (IE) | 2012-12-25 | — | — | US | disclosed |
| US-20100066243-A1 | ORGANIC ELECTROLUMINESCENT DEVICE AND INDOLE DERIVATIVE | FUJIFILM CORPORATION (JP) | 2010-03-18 | — | — | US | disclosed |
| US-20100066243-A1 | ORGANIC ELECTROLUMINESCENT DEVICE AND INDOLE DERIVATIVE | FUJIFILM CORPORATION (JP) | 2010-03-18 | — | — | US | disclosed |
| US-20100026174-A1 | ORGANIC ELECTROLUMINESCENT DEVICE | FUJIFILM CORPORATION (JP) | 2010-02-04 | — | — | US | disclosed |
| US-20100026174-A1 | ORGANIC ELECTROLUMINESCENT DEVICE | FUJIFILM CORPORATION (JP) | 2010-02-04 | — | — | US | disclosed |
| WO-2008066195-A1 | ORGANIC ELECTROLUMINESCENT DEVICE AND INDOLE DERIVATIVE | FUJIFILM CORPORATION (JP) | 2008-06-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100066243-A1 | ORGANIC ELECTROLUMINESCENT DEVICE AND INDOLE DERIVATIVE | IDO1, IDO2, L1CAM | ALDH1A1 101/4885TSHR 1593/4885HDAC10 1020/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.