Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | GBA1 | P04062 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.39 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.39 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.39 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.39 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.39 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.39 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6412508 | 0.84 | KDM4E (0.53) | SMN1; SMN2ALDH1A1KDM4EGAAHPGD | |
| SCHEMBL3500082 | 0.77 | HDAC1 (0.41) | KDM4EGBA1GPR119GABRA1GABRG2 | |
| SCHEMBL13425981 | 0.74 | PTGS2 (0.46) | SMN1; SMN2ALDH1A1KDM4EHPGDGPR119 | |
| SCHEMBL13426488 | 0.74 | PDE4B (0.43) | HPGDL3MBTL1KMT2AMEN1NPC1 | |
| SCHEMBL13425893 | 0.74 | PDE4B (0.43) | ALDH1A1HPGDTP53HSD17B10POLB | |
| SCHEMBL13425885 | 0.74 | PTGS2 (0.43) | SMN1; SMN2ALDH1A1KDM4EGAAHPGD | |
| SCHEMBL13426485 | 0.74 | KDM4E (0.43) | SMN1; SMN2ALDH1A1KDM4EHPGDKMT2A | |
| SCHEMBL13425845 | 0.74 | TSHR (0.43) | SMN1; SMN2ALDH1A1KDM4EHPGDKMT2A | |
| SCHEMBL13425942 | 0.73 | HSP90AA1 (0.41) | SMN1; SMN2GAAGPR119KMT2AMEN1 | |
| SCHEMBL13425935 | 0.73 | PTGS2 (0.47) | GAANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010046780-A2 | ANTI VIRAL COMPOUNDS | INSTITUT PASTEUR KOREA (KR) | 2010-04-29 | — | — | WO | disclosed |