Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 11/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.53 |
| ▸ | GAA | P10253 | 7/20 | 0.53 |
| ▸ | HPGD | P15428 | 6/20 | 0.53 |
| ▸ | GLA | P06280 | 3/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.50 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | FUBP1 | Q96AE4 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.43 |
| ▸ | MYC | P01106 | 1/20 | 0.42 |
| ▸ | MAX | P61244 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13425864 | 0.84 | SMN1; SMN2 (0.44) | KDM4EALDH1A1GAAHPGDGLA | |
| SCHEMBL25519570 | 0.75 | MAP2K4 (0.40) | KDM4EALDH1A1GAAHPGDGLA | |
| SCHEMBL3500082 | 0.74 | HDAC1 (0.41) | KDM4EMAPT | |
| SCHEMBL3259727 | 0.74 | KDM4E (0.62) | KDM4EALDH1A1GAAHPGDGLA | |
| SCHEMBL14014121 | 0.68 | KDM4E (0.78) | KDM4EALDH1A1GAAHPGDGLA | |
| SCHEMBL24148229 | 0.68 | MAP2K4 (0.45) | KDM4EALDH1A1HPGDRXFP1MEN1 | |
| SCHEMBL14008902 | 0.67 | KDM4E (0.49) | KDM4EALDH1A1GAAHPGDGLA | |
| SCHEMBL1718395 | 0.66 | KDM4E (0.78) | KDM4EALDH1A1GAAHPGDGLA | |
| SCHEMBL5212643 | 0.66 | ALDH1A1 (0.49) | KDM4EALDH1A1GAAHPGDGLA | |
| SCHEMBL3277995 | 0.66 | KDM4E (1.00) | KDM4EALDH1A1GAAHPGDGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050048092-A1 | Thienyl-pyrazoles and their use for controlling pests | WADA KATSUAKI (JP) | 2005-03-03 | — | — | US | disclosed |
| US-6593358-B1 | Method for controlling pests, comprising the step of allowing a pesticidally effective amount of one or more compounds selected from the group consisting of one or more compounds of the formula (Ia) according to claim 2 and one or compounds | NIHON BAYER AGROCHEM K.K. (JP) | 2003-07-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050048092-A1 | Thienyl-pyrazoles and their use for controlling pests | CBR3, C1S, CYP4B1 | KDM4E 1709/4885ALDH1A1 534/4885GAA 4475/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.