Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.50 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | EGFR | P00533 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.42 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2442625 | 0.86 | HRH4 (0.50) | HRH4HRH3ALDH1A1KDM4ESMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL2444782 | 0.85 | HRH4 (0.49) | HRH4HRH3ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL2442628 | 0.79 | HRH4 (0.58) | HRH4HRH3ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL13426234 | 0.79 | HRH4 (0.57) | HRH4HRH3ALDH1A1KDM4EEGFR | |
| Hydrochloric Acid SCHEMBL2444785 | 0.78 | HRH4 (0.57) | HRH4HRH3ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL13426298 | 0.75 | ALDH1A1 (0.51) | ALDH1A1KDM4ESMN1; SMN2LMNASLC22A2 | |
| SCHEMBL13426319 | 0.74 | ALDH1A1 (0.46) | ALDH1A1KDM4ESMN1; SMN2LMNASLC22A2 | |
| SCHEMBL20982609 | 0.73 | HDAC6 (0.52) | ALDH1A1SMN1; SMN2LMNASLC22A2SLC22A1 | |
| SCHEMBL13426153 | 0.73 | LMNA (0.58) | ALDH1A1SMN1; SMN2LMNASLC22A2SLC22A1 | |
| SCHEMBL13426304 | 0.71 | KDM4E (0.56) | ALDH1A1KDM4ESMN1; SMN2LMNAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100061928-A1 | LABELLED ANALOGUES OF HALOBENZAMIDES AS RADIOPHARMACEUTICALS | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2010-03-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100061928-A1 | LABELLED ANALOGUES OF HALOBENZAMIDES AS RADIOPHARMACEUTICALS | HRH3, H1-3, HRH4 | HRH4 3/4885HRH3 1/4885ALDH1A1 794/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.