Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 8/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.35 |
| ▸ | HPGD | P15428 | 6/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.35 |
| ▸ | MEN1 | O00255 | 5/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 2/20 | 0.34 |
| ▸ | NCOA2 | Q15596 | 2/20 | 0.34 |
| ▸ | NCOA1 | Q15788 | 2/20 | 0.34 |
| ▸ | NCOA3 | Q9Y6Q9 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.33 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.33 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10122774 | 1.00 | MAPT (0.40) | MAPTNPSR1ALDH1A1TSHRPKM | |
| SCHEMBL12898260 | 1.00 | MAPT (0.40) | MAPTNPSR1ALDH1A1TSHRPKM | |
| SCHEMBL30132089 | 0.86 | MAPT (0.48) | MAPTNPSR1ALDH1A1TSHRPKM | |
| SCHEMBL14599149 | 0.86 | MAPT (0.48) | MAPTNPSR1ALDH1A1TSHRPKM | |
| SCHEMBL13458992 | 0.86 | MAPT (0.48) | MAPTNPSR1ALDH1A1TSHRPKM | |
| SCHEMBL63297 | 0.86 | MAPT (0.48) | MAPTNPSR1ALDH1A1TSHRPKM | |
| SCHEMBL7915441 | 0.86 | MAPT (0.48) | MAPTNPSR1ALDH1A1TSHRPKM | |
| SCHEMBL432548 | 0.86 | MAPT (0.48) | MAPTNPSR1ALDH1A1TSHRPKM | |
| Ammonia Solution, Strong SCHEMBL1883384 | 0.84 | MAPT (0.47) | MAPTNPSR1ALDH1A1TSHRPKM | |
| Ammonia Solution, Strong SCHEMBL21839 | 0.84 | MAPT (0.47) | MAPTNPSR1ALDH1A1TSHRPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8766238-B2 | Polymeric anions/cations | MERCK PATENT GMBH (DE) | 2014-07-01 | — | — | US | disclosed |
| US-20100059740-A1 | POLYMERIC ANIONS/CATIONS | MERCK PATENT GMBH (DE) | 2010-03-11 | — | — | US | disclosed |