Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 8/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.35 |
| ▸ | HPGD | P15428 | 6/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.35 |
| ▸ | MEN1 | O00255 | 5/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 2/20 | 0.34 |
| ▸ | NCOA2 | Q15596 | 2/20 | 0.34 |
| ▸ | NCOA1 | Q15788 | 2/20 | 0.34 |
| ▸ | NCOA3 | Q9Y6Q9 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.33 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.33 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12898260 | 1.00 | MAPT (0.40) | MAPTNPSR1ALDH1A1TSHRPKM | |
| SCHEMBL13428197 | 1.00 | MAPT (0.40) | MAPTNPSR1ALDH1A1TSHRPKM | |
| SCHEMBL30132089 | 0.86 | MAPT (0.48) | MAPTNPSR1ALDH1A1TSHRPKM | |
| SCHEMBL14599149 | 0.86 | MAPT (0.48) | MAPTNPSR1ALDH1A1TSHRPKM | |
| SCHEMBL13458992 | 0.86 | MAPT (0.48) | MAPTNPSR1ALDH1A1TSHRPKM | |
| SCHEMBL63297 | 0.86 | MAPT (0.48) | MAPTNPSR1ALDH1A1TSHRPKM | |
| SCHEMBL7915441 | 0.86 | MAPT (0.48) | MAPTNPSR1ALDH1A1TSHRPKM | |
| SCHEMBL432548 | 0.86 | MAPT (0.48) | MAPTNPSR1ALDH1A1TSHRPKM | |
| Ammonia Solution, Strong SCHEMBL1883384 | 0.84 | MAPT (0.47) | MAPTNPSR1ALDH1A1TSHRPKM | |
| Ammonia Solution, Strong SCHEMBL21839 | 0.84 | MAPT (0.47) | MAPTNPSR1ALDH1A1TSHRPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8097442-B2 | Laccases, nucleic acids encoding them and methods for making and using them | VERENIUM CORPORATION (US) | 2012-01-17 | — | — | US | disclosed |
| US-20100267110-A1 | LACCASES, NUCLEIC ACIDS ENCODING THEM AND METHODS FOR MAKING AND USING THEM | VERENIUM CORPORATION (US) | 2010-10-21 | — | — | US | disclosed |
| US-7741089-B2 | Laccases, nucleic acids encoding them and methods for making and using them | VERENIUM CORPORATION (US) | 2010-06-22 | — | — | US | disclosed |
| US-7445908-B2 | Detection of oxidizing agents in urine | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY (US) | 2008-11-04 | — | — | US | disclosed |
| US-20070105112-A1 | Laccases, nucleic acids encoding them and methods for making and using them | VERENIUM CORPORATION | 2007-05-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100267110-A1 | LACCASES, NUCLEIC ACIDS ENCODING THEM AND METHODS FOR MAKING AND USING THEM | RNGTT, RNASEL, UNG | MAPT 3988/4885NPSR1 2325/4885ALDH1A1 704/4885 |
| US-20070105112-A1 | Laccases, nucleic acids encoding them and methods for making and using them | RNGTT, TRDMT1, DNTT | MAPT 1409/4885NPSR1 3167/4885ALDH1A1 1031/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.