SCHEMBL13428240

SCHEMBL13428240

c1ccc2c(c1)CCCN2c1ccc2c(-c3cccc4ccccc34)c3ccc(N4CCCc5ccccc54)cc3c(-c3cccc4ccccc34)c2c1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.39
ROCK1 Q13464 1/20 0.39
JAK2 O60674 1/20 0.39
JAK3 P52333 1/20 0.39
PTK2 Q05397 1/20 0.39
EED O75530 1/20 0.39
NUDT1 P36639 1/20 0.38
CES1 P23141 2/20 0.37
TUBB4A P04350 2/20 0.37
TUBB P07437 2/20 0.37
TUBA3C P0DPH7 2/20 0.37
TUBA1B P68363 2/20 0.37
TUBA4A P68366 2/20 0.37
TUBB4B P68371 2/20 0.37
TUBB3 Q13509 2/20 0.37
TUBB2A Q13885 2/20 0.37
TUBB8 Q3ZCM7 2/20 0.37
TUBA3E Q6PEY2 2/20 0.37
TUBA1A Q71U36 2/20 0.37
TUBA1C Q9BQE3 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13426454 1.00 L3MBTL1 (0.39) L3MBTL1ROCK1JAK2JAK3PTK2
SCHEMBL13426743 0.96 L3MBTL1 (0.37) L3MBTL1ROCK1JAK2JAK3PTK2
SCHEMBL13426529 0.95 L3MBTL1 (0.38) L3MBTL1ROCK1JAK2JAK3PTK2
SCHEMBL13428245 0.94 LMNA (0.39) L3MBTL1ROCK1JAK2JAK3PTK2
SCHEMBL13426720 0.94 JAK2 (0.38) L3MBTL1ROCK1JAK2JAK3PTK2
SCHEMBL13426550 0.94 LMNA (0.39) L3MBTL1ROCK1JAK2JAK3PTK2
SCHEMBL13426748 0.93 LMNA (0.38) L3MBTL1ROCK1JAK2JAK3PTK2
SCHEMBL13426791 0.93 EED (0.39) L3MBTL1ROCK1JAK2JAK3PTK2
SCHEMBL13426751 0.93 L3MBTL1 (0.35) L3MBTL1ROCK1JAK2JAK3PTK2
SCHEMBL13303899 0.93 HSD17B10 (0.37) ROCK1SIGMAR1ALDH1A1LMNAKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100051106-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same GRACEL DISPLAY INC. (KR) 2010-03-04 US disclosed
US-20100051106-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same GRACEL DISPLAY INC. (KR) 2010-03-04 US disclosed
EP-2141214-A2 Novel organic electroluminescent compounds and organic electroluminescent device using the same Gracel Display Inc. (KR) 2010-01-06 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100051106-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same RPL36, RPL39, RPL36A L3MBTL1 1117/4885ROCK1 3925/4885JAK2 3180/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.