SCHEMBL13428273

SCHEMBL13428273

c1ccc2c(c1)Oc1ccccc1N2c1ccc2c(-c3ccc4ccccc4c3)c3ccc(N4c5ccccc5Oc5ccccc54)cc3c(-c3ccc4ccccc4c3)c2c1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSP90AA1 P07900 1/20 0.36
SMN1; SMN2 Q16637 2/20 0.35
MAPT P10636 1/20 0.35
NPSR1 Q6W5P4 1/20 0.35
MAPK9 P45984 3/20 0.33
MAPK10 P53779 3/20 0.33
MAPK8 P45983 1/20 0.33
PDE9A O76083 1/20 0.32
CYP1A1 P04798 1/20 0.32
CYP1B1 Q16678 1/20 0.32
GSTP1 P09211 1/20 0.32
ESR1 P03372 1/20 0.32
ESR2 Q92731 1/20 0.32
UTRN P46939 1/20 0.32
LPL P06858 1/20 0.31
LIPG Q9Y5X9 1/20 0.31
CYP1A2 P05177 1/20 0.31
ALOX5 P09917 1/20 0.31
GPR84 Q9NQS5 1/20 0.31
POLB P06746 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13427222 1.00 HSP90AA1 (0.36) HSP90AA1SMN1; SMN2MAPTNPSR1MAPK9
SCHEMBL13427255 0.96 SMN1; SMN2 (0.33) HSP90AA1SMN1; SMN2MAPTNPSR1MAPK9
SCHEMBL13427278 0.96 ESR1 (0.36) HSP90AA1SMN1; SMN2MAPTNPSR1MAPK9
SCHEMBL13428275 0.96 SMN1; SMN2 (0.33) HSP90AA1SMN1; SMN2MAPTNPSR1MAPK9
SCHEMBL13427268 0.95 HSD17B1 (0.36) HSP90AA1SMN1; SMN2MAPTNPSR1MAPK9
SCHEMBL13427251 0.95 HSD17B1 (0.36) HSP90AA1SMN1; SMN2MAPTNPSR1MAPK9
SCHEMBL13009422 0.95 GPR84 (0.36) HSP90AA1SMN1; SMN2MAPTNPSR1ESR1
SCHEMBL13427267 0.95 ESR1 (0.34) HSP90AA1SMN1; SMN2MAPTNPSR1CYP1A1
SCHEMBL13009059 0.95 ESR1 (0.36) HSP90AA1SMN1; SMN2MAPTNPSR1MAPK9
SCHEMBL13427284 0.93 SMN1; SMN2 (0.39) HSP90AA1SMN1; SMN2MAPTNPSR1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100051106-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same GRACEL DISPLAY INC. (KR) 2010-03-04 US disclosed
US-20100051106-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same GRACEL DISPLAY INC. (KR) 2010-03-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100051106-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same RPL36, RPL39, RPL36A HSP90AA1 4086/4885SMN1; SMN2 3636/4885MAPT 3713/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.