Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SNCA | P37840 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 3/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | NSD2 | O96028 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.33 |
| ▸ | RAD52 | P43351 | 1/20 | 0.33 |
| ▸ | INSR | P06213 | 1/20 | 0.31 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14454740 | 0.78 | SNCA (0.64) | SNCAPOLBMAPTHTTNPSR1 | |
| SCHEMBL13194374 | 0.78 | SNCA (0.64) | SNCAPOLBMAPTHTTNPSR1 | |
| Iodide SCHEMBL10537076 | 0.74 | NPC1 (0.52) | SNCAPOLBALDH1A1PKMMAPT | |
| Iodide SCHEMBL10537077 | 0.74 | NPC1 (0.52) | SNCAPOLBALDH1A1PKMMAPT | |
| SCHEMBL5701141 | 0.72 | INSR (0.61) | POLBALDH1A1PKMMAPTHTT | |
| SCHEMBL5701145 | 0.72 | INSR (0.61) | POLBALDH1A1PKMMAPTHTT | |
| Iodide SCHEMBL1405415 | 0.70 | NPC1 (0.44) | SNCAPOLBALDH1A1PKMMAPT | |
| Perchlorate SCHEMBL1532917 | 0.70 | HTT (0.60) | POLBALDH1A1PKMMAPTHTT | |
| Perchlorate SCHEMBL1532916 | 0.70 | HTT (0.60) | POLBALDH1A1PKMMAPTHTT | |
| SCHEMBL13171852 | 0.69 | INSR (0.53) | SNCAPOLBALDH1A1PKMMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8766238-B2 | Polymeric anions/cations | MERCK PATENT GMBH (DE) | 2014-07-01 | — | — | US | disclosed |
| US-20100059740-A1 | POLYMERIC ANIONS/CATIONS | MERCK PATENT GMBH (DE) | 2010-03-11 | — | — | US | disclosed |