Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SNCA | P37840 | 1/20 | 0.64 |
| ▸ | INSR | P06213 | 10/20 | 0.49 |
| ▸ | ADRB2 | P07550 | 3/20 | 0.45 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | NSD2 | O96028 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13194374 | 1.00 | SNCA (0.64) | SNCAINSRADRB2ADRB1POLB | |
| SCHEMBL13171852 | 0.86 | INSR (0.53) | SNCAINSRPOLBMAPTNPSR1 | |
| SCHEMBL13294127 | 0.82 | SNCA (0.43) | SNCAINSRPOLBHTTL3MBTL1 | |
| SCHEMBL14706832 | 0.81 | SNCA (0.48) | SNCAINSRPOLBMAPTNPSR1 | |
| SCHEMBL1105806 | 0.81 | SNCA (0.48) | SNCAINSRPOLBMAPTNPSR1 | |
| Iodide SCHEMBL31063609 | 0.79 | SNCA (0.97) | SNCAINSRADRB2ADRB1POLB | |
| SCHEMBL13428302 | 0.78 | SNCA (0.41) | SNCAINSRADRB2ADRB1POLB | |
| Iodide SCHEMBL31063717 | 0.78 | SNCA (1.00) | SNCAINSRADRB2ADRB1POLB | |
| Iodide SCHEMBL31063626 | 0.75 | SNCA (0.80) | SNCAINSRADRB2ADRB1POLB | |
| SCHEMBL13989159 | 0.74 | KMT2A (0.53) | POLBMAPTHTTMAPK1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070154899-A1 | Biodetection by nucleic acid-templated chemistry | ENSEMBLE THERAPEUTICS CORPORATION | 2007-07-05 | — | — | US | disclosed |
| US-20070154899-A1 | Biodetection by nucleic acid-templated chemistry | ENSEMBLE THERAPEUTICS CORPORATION | 2007-07-05 | — | — | US | disclosed |