SCHEMBL13428343

SCHEMBL13428343

c1ccc2c(c1)Sc1ccccc1N2c1cccc2c(-c3ccc4ccccc4c3)c3c(N4c5ccccc5Sc5ccccc54)cccc3c(-c3ccc4ccccc4c3)c12

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BCHE P06276 9/20 0.42
SLC6A3 Q01959 2/20 0.39
HTR2C P28335 1/20 0.39
ADRA1A P35348 1/20 0.39
HTR2B P41595 1/20 0.39
HTR6 P50406 1/20 0.39
ACHE P22303 1/20 0.39
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38
NPSR1 Q6W5P4 1/20 0.38
MAOA P21397 1/20 0.34
HSD17B1 P14061 1/20 0.34
HSD17B2 P37059 1/20 0.34
CYP2D6 P10635 2/20 0.33
CYP2C19 P33261 2/20 0.33
CYP1A2 P05177 2/20 0.33
KDM4E B2RXH2 1/20 0.33
CYP3A4 P08684 1/20 0.33
MAPT P10636 1/20 0.33
HIF1A Q16665 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13540254 0.84 BCHE (0.32) BCHESLC6A3HTR2CADRA1AHTR2B
SCHEMBL13008474 0.82 MAOA (0.40) BCHESLC6A3HTR2CHTR2BHTR6
SCHEMBL13428376 0.82 AKT1 (0.45) MEN1KMT2AHSD17B1HSD17B2PDE9A
SCHEMBL13008494 0.82 BCHE (0.33) BCHESLC6A3HTR2CADRA1AHTR2B
SCHEMBL13428333 0.81 CYP3A4 (0.36) MEN1KMT2AHSD17B1HSD17B2CYP1A2
SCHEMBL13428350 0.81 SMN1; SMN2 (0.36) HTR2BNPSR1HSD17B1HSD17B2CYP1A2
SCHEMBL13428355 0.78 MAPT (0.38) SLC6A3MEN1KMT2AHSD17B1HSD17B2
SCHEMBL13428362 0.78 BCHE (0.45) BCHESLC6A3ACHEMAOACYP2D6
SCHEMBL13408884 0.77 BCHE (0.39) BCHESLC6A3HTR2CADRA1AHTR2B
SCHEMBL13009396 0.77 BCHE (0.41) BCHESLC6A3HTR2CADRA1AHTR2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100051106-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same GRACEL DISPLAY INC. (KR) 2010-03-04 US disclosed
US-20100051106-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same GRACEL DISPLAY INC. (KR) 2010-03-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100051106-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same RPL36, RPL39, RPL36A BCHE 3337/4885SLC6A3 2644/4885HTR2C 4026/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.