SCHEMBL13428355

SCHEMBL13428355

CC1(C)c2ccccc2N(c2cccc3c(-c4ccc5ccccc5c4)c4c(N5c6ccccc6C(C)(C)c6ccccc65)cccc4c(-c4ccc5ccccc5c4)c23)c2ccccc21

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.38
KDM4E B2RXH2 4/20 0.38
MEN1 O00255 3/20 0.38
KMT2A Q03164 3/20 0.38
MAPK1 P28482 1/20 0.38
ALDH1A1 P00352 2/20 0.37
HTT P42858 1/20 0.37
LPL P06858 1/20 0.33
LIPG Q9Y5X9 1/20 0.33
GAA P10253 1/20 0.33
IKBKB O14920 1/20 0.33
HSD17B1 P14061 1/20 0.33
HSD17B2 P37059 1/20 0.33
DRD2 P14416 2/20 0.32
DRD1 P21728 2/20 0.32
HTR2A P28223 2/20 0.32
PTGER3 P43115 5/20 0.32
AKT1 P31749 1/20 0.32
PDE9A O76083 1/20 0.32
LMNA P02545 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13428353 0.83 KMT2A (0.37) MAPTKDM4EMEN1KMT2AMAPK1
SCHEMBL13428376 0.82 AKT1 (0.45) MEN1KMT2AIKBKBHSD17B1HSD17B2
SCHEMBL13428350 0.81 SMN1; SMN2 (0.36) MAPTKDM4EMAPK1LPLLIPG
SCHEMBL13352821 0.81 MAPT (0.36) MAPTKDM4EMEN1KMT2AMAPK1
SCHEMBL13008471 0.80 KMT2A (0.44) MAPTKDM4EMEN1KMT2AMAPK1
SCHEMBL13408887 0.79 KDM4E (0.35) MAPTKDM4EMEN1KMT2AMAPK1
SCHEMBL13428333 0.78 CYP3A4 (0.36) MEN1KMT2AIKBKBHSD17B1HSD17B2
SCHEMBL13428343 0.78 BCHE (0.42) MAPTKDM4EMEN1KMT2AHSD17B1
SCHEMBL13371456 0.78 MAPT (0.34) MAPTKDM4EMEN1KMT2AMAPK1
SCHEMBL13008313 0.78 KMT2A (0.36) MAPTKDM4EMEN1KMT2AMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100051106-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same GRACEL DISPLAY INC. (KR) 2010-03-04 US disclosed
US-20100051106-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same GRACEL DISPLAY INC. (KR) 2010-03-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100051106-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same RPL36, RPL39, RPL36A MAPT 3713/4885KDM4E 4138/4885MEN1 3994/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.