Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | MAOB | P27338 | 6/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.42 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12238280 | 0.87 | PPARD (0.61) | PPARDMEN1KMT2AMAOBTSHR | |
| SCHEMBL2326829 | 0.86 | PPARD (0.59) | PPARDMEN1KMT2AMAOBTSHR | |
| Lithium Ion SCHEMBL2326822 | 0.84 | PPARD (0.45) | PPARDMAOBTSHRMAPK1MAOA | |
| SCHEMBL18823988 | 0.83 | KDM4E (0.57) | MEN1KMT2AMAOBTSHRALDH1A1 | |
| SCHEMBL2332124 | 0.82 | HPGD (0.54) | PPARDMEN1KMT2AMAPK1ALDH1A1 | |
| SCHEMBL16360632 | 0.79 | ALDH1A1 (0.57) | PPARDMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL312677 | 0.78 | ALDH1A1 (0.65) | MEN1KMT2AMAOBMAPK1ALDH1A1 | |
| SCHEMBL29976235 | 0.78 | ALDH1A1 (0.65) | MEN1KMT2AMAOBMAPK1ALDH1A1 | |
| SCHEMBL656717 | 0.77 | MEN1 (0.56) | MEN1KMT2AALDH1A1LMNAMAPT | |
| SCHEMBL7344872 | 0.77 | MCL1 (0.49) | MEN1KMT2AMAPK1MAPK10ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2356092-B1 | BIOSYNTHETICALLY GENERATED PYRROLINE-CARBOXY-LYSINE AND SITE SPECIFIC PROTEIN MODIFICATIONS VIA CHEMICAL DERIVATIZATION OF PYRROLINE-CARBOXY-LYSINE AND PYRROLYSINE RESIDUES | IRM LLC (BM) | 2014-04-16 | — | — | EP | disclosed |
| WO-2010048582-A1 | BIOSYNTHETICALLY GENERATED PYRROLINE-CARBOXY-LYSINE AND SITE SPECIFIC PROTEIN MODIFICATIONS VIA CHEMICAL DERIVATIZATION OF PYRROLINE-CARBOXY-LYSINE AND PYRROLYSINE RESIDUES | IRM LLC (BM) | 2010-04-29 | — | — | WO | disclosed |