SCHEMBL13428353

SCHEMBL13428353

CC1(C)c2ccccc2N(c2cccc3c(-c4ccccc4)c4c(N5c6ccccc6C(C)(C)c6ccccc65)cccc4c(-c4ccccc4)c23)c2ccccc21

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 6/20 0.37
MAPT P10636 6/20 0.37
MEN1 O00255 5/20 0.37
KDM4E B2RXH2 2/20 0.37
MAPK1 P28482 1/20 0.37
SLC6A4 P31645 2/20 0.36
SLC6A2 P23975 1/20 0.36
CYP2D6 P10635 2/20 0.35
CYP1A2 P05177 1/20 0.35
LMNA P02545 3/20 0.33
HTT P42858 3/20 0.33
GAA P10253 2/20 0.32
ITGB2 P05107 1/20 0.32
ICAM1 P05362 1/20 0.32
ITGAL P20701 1/20 0.32
THRB P10828 2/20 0.32
RECQL P46063 2/20 0.32
NPSR1 Q6W5P4 2/20 0.32
ACHE P22303 1/20 0.32
NPC1 O15118 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13428372 0.91 KMT2A (0.35) KMT2AMAPTMEN1KDM4EMAPK1
SCHEMBL13428355 0.83 MAPT (0.38) KMT2AMAPTMEN1KDM4EMAPK1
SCHEMBL13008471 0.81 KMT2A (0.44) KMT2AMAPTMEN1KDM4EMAPK1
SCHEMBL13428367 0.80 TERT (0.36) KMT2AMAPTMEN1KDM4ECYP1A2
SCHEMBL13231590 0.79 KMT2A (0.46) KMT2AMAPTMEN1KDM4EMAPK1
SCHEMBL13428351 0.78 P2RX4 (0.37) MAPTKDM4ECYP1A2LMNAPOLB
SCHEMBL13231539 0.75 KMT2A (0.47) KMT2AMAPTMEN1KDM4EMAPK1
SCHEMBL22501751 0.75 MAPT (0.54) KMT2AMAPTMEN1KDM4EMAPK1
SCHEMBL30825127 0.75 MAPT (0.54) KMT2AMAPTMEN1KDM4EMAPK1
SCHEMBL12723365 0.75 KMT2A (0.33) KMT2AMAPTMEN1KDM4EMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100051106-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same GRACEL DISPLAY INC. (KR) 2010-03-04 US disclosed
US-20100051106-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same GRACEL DISPLAY INC. (KR) 2010-03-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100051106-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same RPL36, RPL39, RPL36A KMT2A 2323/4885MAPT 3713/4885MEN1 3994/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.