Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.45 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.45 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.45 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | PIM1 | P11309 | 1/20 | 0.42 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3225286 | 0.97 | RAB9A (0.49) | RAB9ASMN1; SMN2HDAC3HDAC4HDAC1 | |
| SCHEMBL3225269 | 0.97 | RAB9A (0.49) | RAB9ASMN1; SMN2HDAC3HDAC4HDAC1 | |
| SCHEMBL13429130 | 0.90 | HDAC8 (0.58) | RAB9ASMN1; SMN2HDAC3HDAC4HDAC1 | |
| SCHEMBL13429097 | 0.87 | HDAC1 (0.59) | RAB9ASMN1; SMN2HDAC3HDAC4HDAC1 | |
| SCHEMBL13428582 | 0.87 | KMT2A (0.48) | RAB9ASMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL8171035 | 0.86 | SMN1; SMN2 (0.48) | RAB9ASMN1; SMN2HDAC3HDAC4HDAC1 | |
| Hydrochloric Acid SCHEMBL3227377 | 0.86 | HDAC1 (0.58) | RAB9ASMN1; SMN2HDAC3HDAC4HDAC1 | |
| Hydrochloric Acid SCHEMBL3227393 | 0.86 | HDAC1 (0.58) | RAB9ASMN1; SMN2HDAC3HDAC4HDAC1 | |
| SCHEMBL13428460 | 0.84 | DRD4 (0.46) | RAB9AALDH1A1KDM4ENPC1L3MBTL1 | |
| SCHEMBL13428579 | 0.83 | ALDH1A1 (0.42) | RAB9AALDH1A1KDM4ENPC1PIM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100069388-A1 | N-HYDROXYACRYLAMIDE COMPOUNDS | ASTELLAS PHARMA INC. (JP) | 2010-03-18 | — | — | US | disclosed |
| US-20100069388-A1 | N-HYDROXYACRYLAMIDE COMPOUNDS | ASTELLAS PHARMA INC. (JP) | 2010-03-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100069388-A1 | N-HYDROXYACRYLAMIDE COMPOUNDS | HDAC1, HDAC11, HDAC2 | RAB9A 4190/4885SMN1; SMN2 3352/4885HDAC3 4/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.