SCHEMBL134286

SCHEMBL134286

O=C(c1ccc2c(c1)C1(c3ccccc3-c3ccccc31)c1ccccc1-2)c1ccc2c(c1)C1(c3ccccc3-2)c2ccccc2-c2ccc(C(=O)c3ccc4c(c3)C3(c5ccccc5-c5ccccc53)c3ccccc3-4)cc21

nearest known ligand 0.58

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
PDK2 Q15119 18/20 0.58
TDP1 Q9NUW8 2/20 0.42
THRB P10828 1/20 0.42
ATM Q13315 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL134285 1.00 PDK2 (0.58) PDK2TDP1THRBATML3MBTL1
SCHEMBL29114 1.00 PDK2 (0.58) PDK2TDP1THRBATML3MBTL1
SCHEMBL12337045 0.98 PDK2 (0.60) PDK2TDP1THRBATML3MBTL1
SCHEMBL13702054 0.96 PDK2 (0.55) PDK2TDP1THRBATML3MBTL1
SCHEMBL13702055 0.95 PDK2 (0.57) PDK2TDP1THRBATML3MBTL1
SCHEMBL12200611 0.95 PDK2 (0.54) PDK2TDP1THRB
SCHEMBL133477 0.95 PDK2 (0.66) PDK2TDP1THRBATML3MBTL1
SCHEMBL1552743 0.95 PDK2 (0.66) PDK2TDP1THRBATML3MBTL1
SCHEMBL18900537 0.92 PDK2 (0.51) PDK2TDP1THRB
SCHEMBL4253936 0.90 PDK2 (0.50) PDK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11322696-B2 Metal complexes MERCK PATENT GMBH (DE) 2022-05-03 US disclosed
US-10636990-B2 Organic electroluminescence device MERCK PATENT GMBH (DE) 2020-04-28 US disclosed
EP-2243177-B1 PHOSPHORESCENT OLED HAVING DOUBLE HOLE-BLOCKING LAYERS GLOBAL OLED TECHNOLOGY LLC (US) 2019-05-15 EP disclosed
US-20170309855-A1 ORGANIC ELECTROLUMINESCENCE DEVICE MERCK PATENT GMBH (DE) 2017-10-26 US disclosed
US-20170309855-A1 ORGANIC ELECTROLUMINESCENCE DEVICE MERCK PATENT GMBH (DE) 2017-10-26 US disclosed
US-9735385-B2 Organic electroluminescence device MERCK PATENT GMBH (DE) 2017-08-15 US disclosed
US-9735385-B2 Organic electroluminescence device MERCK PATENT GMBH (DE) 2017-08-15 US disclosed
EP-2791275-B1 ORGANIC SENSITIZERS FOR UP-CONVERSION MERCK PATENT GMBH (DE) 2017-05-31 EP disclosed
US-9653687-B2 Materials for organic electroluminescent devices MERCK PATENT GMBH (DE) 2017-05-16 US disclosed
US-9653687-B2 Materials for organic electroluminescent devices MERCK PATENT GMBH (DE) 2017-05-16 US disclosed
US-20110284831-A1 ORGANIC ELECTROLUMINESCENCE DEVICE MERCK PATENT GMBH (DE) 2011-11-24 US disclosed
US-20110284831-A1 ORGANIC ELECTROLUMINESCENCE DEVICE MERCK PATENT GMBH (DE) 2011-11-24 US disclosed
US-20110108818-A1 ORGANIC ELECTROLUMINESCENCE DEVICE MERCK PATENT GMBH (DE) 2011-05-12 US disclosed
US-20110108818-A1 ORGANIC ELECTROLUMINESCENCE DEVICE MERCK PATENT GMBH (DE) 2011-05-12 US disclosed
EP-2281861-A2 Mixture of organic emission-enabled semiconductors and matrix materials, use of same and electronic components containing same Merck Patent GmbH (DE) 2011-02-09 EP disclosed
WO-2009097108-A1 PHOSPHORESCENT OLED HAVING DOUBLE HOLE-BLOCKING LAYERS EASTMAN KODAK COMPANY (US) 2009-08-06 WO disclosed
US-20090191427-A1 PHOSPHORESCENT OLED HAVING DOUBLE HOLE-BLOCKING LAYERS GLOBAL OLED TECHNOLOGY LLC 2009-07-30 US disclosed
US-20090191427-A1 PHOSPHORESCENT OLED HAVING DOUBLE HOLE-BLOCKING LAYERS GLOBAL OLED TECHNOLOGY LLC 2009-07-30 US disclosed
US-7345301-B2 Mixtures of matrix materials and organic semiconductors capable of emission, use of the same and electronic components containing said mixtures MERCK PATENT GMBH (DE) 2008-03-18 US disclosed
US-7345301-B2 Mixtures of matrix materials and organic semiconductors capable of emission, use of the same and electronic components containing said mixtures MERCK PATENT GMBH (DE) 2008-03-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11322696-B2 Metal complexes AP1M1, AP3M1, AP2M1 PDK2 2214/4885TDP1 3219/4885THRB 4677/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.