Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 5/20 | 0.66 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.47 |
| ▸ | PTPRC | P08575 | 1/20 | 0.46 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.42 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL133477 | 1.00 | PDK2 (0.66) | PDK2TDP1ATML3MBTL1ALDH1A1 | |
| SCHEMBL12337045 | 0.96 | PDK2 (0.60) | PDK2TDP1ATML3MBTL1ALDH1A1 | |
| SCHEMBL134286 | 0.95 | PDK2 (0.58) | PDK2TDP1ATML3MBTL1THRB | |
| SCHEMBL134285 | 0.95 | PDK2 (0.58) | PDK2TDP1ATML3MBTL1THRB | |
| SCHEMBL29114 | 0.95 | PDK2 (0.58) | PDK2TDP1ATML3MBTL1THRB | |
| SCHEMBL13702055 | 0.93 | PDK2 (0.57) | PDK2TDP1ATML3MBTL1PTPRC | |
| SCHEMBL13702054 | 0.91 | PDK2 (0.55) | PDK2TDP1ATML3MBTL1THRB | |
| SCHEMBL18567976 | 0.91 | PDK2 (0.57) | PDK2TDP1ATML3MBTL1ALDH1A1 | |
| SCHEMBL17928299 | 0.91 | PDK2 (0.57) | PDK2TDP1ATML3MBTL1ALDH1A1 | |
| SCHEMBL12200611 | 0.90 | PDK2 (0.54) | PDK2TDP1THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240228523-A1 | Metal complexes | UDC IRELAND LTD (IE) | 2024-07-11 | — | — | US | disclosed |
| US-9634256-B2 | Electroluminescent devices including organic EIL layer | GLOBAL OLED TECHNOLOGY LLC (US) | 2017-04-25 | — | — | US | disclosed |
| US-9634256-B2 | Electroluminescent devices including organic EIL layer | GLOBAL OLED TECHNOLOGY LLC (US) | 2017-04-25 | — | — | US | disclosed |
| US-20150311447-A1 | ELECTROLUMINESCENT DEVICES INCLUDING ORGANIC EIL LAYER | GLOBAL OLED TECHNOLOGY LLC (US) | 2015-10-29 | — | — | US | disclosed |
| US-9118020-B2 | Electroluminescent devices including organic eil layer | GLOBAL OLED TECHNOLOGY LLC (US) | 2015-08-25 | — | — | US | disclosed |
| US-8188462-B2 | Spirobifluorene derivatives, their preparation and uses thereof | MERCK PATENT GMBH (DE) | 2012-05-29 | — | — | US | disclosed |
| EP-1534661-B1 | SPIROBIFLUORENE DERIVATIVES, THEIR PREPARATION AND USES THEREOF | MERCK PATENT GMBH (DE) | 2011-04-27 | — | — | EP | disclosed |
| US-20100084647-A1 | ELECTROLUMINESCENT DEVICES INCLUDING ORGANIC EIL LAYER | GLOBAL OLED TECHNOLOGY LLC | 2010-04-08 | — | — | US | disclosed |
| US-20090302274-A1 | SPIROBIFLUORENE DERIVATIVES, THEIR PREPARATION AND USES THEREOF | MERCK PATENT GMBH (DE) | 2009-12-10 | — | — | US | disclosed |
| US-7557249-B2 | Spirobifluorene derivatives, their preparation and uses thereof | MERCK PATENT GMBH (DE) | 2009-07-07 | — | — | US | disclosed |
| US-20070252516-A1 | Electroluminescent devices including organic EIL layer | EASTMAN KODAK COMPANY | 2007-11-01 | — | — | US | disclosed |
| US-20060006365-A1 | Spirobifluorene derivatives, their preparation and uses thereof | COVION ORGANIC SEMICONDUCTORS GMBH (DE) | 2006-01-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240228523-A1 | Metal complexes | MCU, IMMT, SOD1 | PDK2 2377/4885TDP1 2252/4885ATM 4257/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.