Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 17/20 | 0.57 |
| ▸ | MAOB | P27338 | 1/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11969115 | 1.00 | MAOA (0.57) | MAOAMAOBCYP3A4CYP2D6KCNH2 | |
| SCHEMBL13428688 | 0.89 | MAOA (0.69) | MAOAMAOBCYP3A4CYP2D6KCNH2 | |
| SCHEMBL11969126 | 0.89 | MAOA (0.69) | MAOAMAOBCYP3A4CYP2D6KCNH2 | |
| SCHEMBL11969868 | 0.88 | MAOA (0.56) | MAOAMAOBCYP3A4CYP2D6KCNH2 | |
| SCHEMBL11969148 | 0.84 | MAOA (0.61) | MAOAMAOBCYP3A4CYP2D6KCNH2 | |
| SCHEMBL11969134 | 0.83 | MAOA (0.58) | MAOAMAOBCYP3A4 | |
| SCHEMBL15458132 | 0.82 | MAOA (0.68) | MAOACYP3A4CYP2D6 | |
| SCHEMBL18410309 | 0.81 | MAOA (0.77) | MAOAMAOBCYP3A4CYP2D6KCNH2 | |
| SCHEMBL16107385 | 0.80 | MAOA (0.60) | MAOAMAOBCYP3A4CYP2D6KCNH2 | |
| SCHEMBL14872043 | 0.80 | MAOA (0.60) | MAOAMAOBCYP3A4CYP2D6KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010036000-A2 | NOVEL OXAZOLIDINONE DERIVATIVES WITH CYCLIC AMIDOXIME OR CYCLIC AMIDRAZONE AND PHARMACEUTICAL COMPOSITIONS THEREOF | LEGOCHEM BIOSCIENCE LTD. (KR) | 2010-04-01 | — | — | WO | disclosed |