Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 17/20 | 0.69 |
| ▸ | MAOB | P27338 | 1/20 | 0.69 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11969126 | 1.00 | MAOA (0.69) | MAOAMAOBKCNH2CYP3A4CYP2D6 | |
| SCHEMBL11969132 | 0.90 | MAOA (0.67) | MAOAMAOBKCNH2CYP3A4CYP2D6 | |
| SCHEMBL13428685 | 0.89 | MAOA (0.68) | MAOAMAOBKCNH2CYP3A4CYP2D6 | |
| SCHEMBL11969343 | 0.89 | MAOA (0.68) | MAOAMAOBKCNH2CYP3A4CYP2D6 | |
| SCHEMBL13428681 | 0.89 | MAOA (0.57) | MAOAMAOBKCNH2CYP3A4CYP2D6 | |
| SCHEMBL11969115 | 0.89 | MAOA (0.57) | MAOAMAOBKCNH2CYP3A4CYP2D6 | |
| SCHEMBL13428684 | 0.86 | MAOA (0.64) | MAOAMAOBKCNH2CYP3A4CYP2D6 | |
| SCHEMBL11969140 | 0.86 | MAOA (0.64) | MAOAMAOBKCNH2CYP3A4CYP2D6 | |
| SCHEMBL11969077 | 0.86 | MAOA (0.64) | MAOAMAOBKCNH2CYP3A4CYP2D6 | |
| SCHEMBL11969409 | 0.85 | MAOA (0.73) | MAOAMAOBKCNH2CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010036000-A2 | NOVEL OXAZOLIDINONE DERIVATIVES WITH CYCLIC AMIDOXIME OR CYCLIC AMIDRAZONE AND PHARMACEUTICAL COMPOSITIONS THEREOF | LEGOCHEM BIOSCIENCE LTD. (KR) | 2010-04-01 | — | — | WO | disclosed |