Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 3/20 | 0.39 |
| ▸ | GRM3 | Q14832 | 2/20 | 0.39 |
| ▸ | SLC1A2 | P43004 | 3/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | GRM8 | O00222 | 1/20 | 0.35 |
| ▸ | GRM6 | O15303 | 1/20 | 0.35 |
| ▸ | APEX1 | P27695 | 1/20 | 0.35 |
| ▸ | GRM5 | P41594 | 1/20 | 0.35 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.35 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.35 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10831643 | 0.78 | IDUA (0.44) | LMNATDP1 | |
| SCHEMBL14875876 | 0.78 | IDUA (0.44) | LMNATDP1 | |
| SCHEMBL11896565 | 0.78 | IDUA (0.44) | LMNATDP1 | |
| SCHEMBL10832395 | 0.78 | IDUA (0.44) | LMNATDP1 | |
| SCHEMBL17509637 | 0.72 | THRB (0.35) | LMNA | |
| SCHEMBL21342535 | 0.72 | TDP1 (0.33) | LMNATDP1 | |
| SCHEMBL28266037 | 0.70 | THRB (0.36) | LMNA | |
| SCHEMBL17509641 | 0.69 | THRB (0.32) | LMNA | |
| SCHEMBL7620028 | 0.69 | THRB (0.39) | LMNA | |
| SCHEMBL13259760 | 0.69 | THRB (0.39) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010045584-A1 | FOLATE TARGETING OF NUCLEOTIDES | ENDOCYTE, INC. (US) | 2010-04-22 | — | — | WO | disclosed |