SCHEMBL7620028

SCHEMBL7620028

OC(O)[C@H]1OC[C@H](O)[C@@H]1O

nearest known ligand 0.39

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.39
LMNA P02545 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13259760 1.00 THRB (0.39) THRBLMNA
SCHEMBL2163059 0.95 THRB (0.39) THRBLMNA
SCHEMBL19439507 0.80 THRB (0.36) THRBLMNA
SCHEMBL10420602 0.80 THRB (0.36) THRBLMNA
SCHEMBL25592953 0.80 THRB (0.36) THRBLMNA
SCHEMBL23028656 0.80 THRB (0.36) THRBLMNA
SCHEMBL13657213 0.80 THRB (0.36) THRBLMNA
SCHEMBL13362009 0.80 THRB (0.36) THRBLMNA
SCHEMBL16601877 0.80 THRB (0.36) THRBLMNA
SCHEMBL5085997 0.80 THRB (0.36) THRBLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-100494208-C Novel phosphorus-containing prodrug METABASIS THERAPEUTICS INC (US) 2009-06-03 CN disclosed
CN-101037450-A Novel phosphorus-containing prodrug METABASIS THERAPEUTICS INC (US) 2007-09-19 CN disclosed
CN-1321999-C Novel phosphorus-containing prodrugs METABASIS THERAPEUTICS INC (US) 2007-06-20 CN disclosed
CN-1733779-A Novel phosphorus-containing prodrug METABASIS THERAPEUTICS INC (US) 2006-02-15 CN disclosed
CN-1353719-A Novel phosphorus-containing prodrugs METABASIS THERAPEUTICS INC (US) 2002-06-12 CN disclosed
EP-1165570-A2 NOVEL PHOSPHORUS-CONTAINING PRODRUGS Metabasis Therapeutics, Inc. (US) 2002-01-02 EP disclosed
WO-2000052015-A2 NOVEL PHOSPHORUS-CONTAINING PRODRUGS METABASIS THERAPEUTICS, INC. (US) 2000-09-08 WO disclosed