Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | P2RY12 | Q9H244 | 17/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13428491 | 0.83 | ALDH1A1 (0.42) | ATMNPC1RAB9A | |
| SCHEMBL13428486 | 0.81 | ALDH1A1 (0.42) | ATMNPC1RAB9A | |
| SCHEMBL13428573 | 0.77 | ALDH1A1 (0.40) | ATMNPC1RAB9A | |
| SCHEMBL13428798 | 0.77 | KDM4E (0.51) | P2RY12 | |
| SCHEMBL13429147 | 0.76 | ALDH1A1 (0.39) | ATMNPC1 | |
| SCHEMBL3222737 | 0.75 | ALDH1A1 (0.52) | RAB9AP2RY12 | |
| SCHEMBL13428779 | 0.75 | CYP1A2 (0.47) | RAB9AP2RY12 | |
| SCHEMBL13428793 | 0.73 | L3MBTL1 (0.44) | P2RY12 | |
| SCHEMBL8184807 | 0.72 | NPC1 (0.41) | ATMNPC1RAB9A | |
| SCHEMBL3227719 | 0.72 | L3MBTL1 (0.47) | P2RY12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100069388-A1 | N-HYDROXYACRYLAMIDE COMPOUNDS | ASTELLAS PHARMA INC. (JP) | 2010-03-18 | — | — | US | disclosed |
| US-20100069388-A1 | N-HYDROXYACRYLAMIDE COMPOUNDS | ASTELLAS PHARMA INC. (JP) | 2010-03-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100069388-A1 | N-HYDROXYACRYLAMIDE COMPOUNDS | HDAC1, HDAC11, HDAC2 | ATM 2546/4885NPC1 4152/4885RAB9A 4190/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.