Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 17/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13456419 | 0.88 | ADORA1 (0.53) | ADORA1HTTKMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL12376471 | 0.83 | ADORA1 (0.63) | ADORA1SLC6A3 | |
| SCHEMBL13428994 | 0.82 | ADORA1 (0.46) | ADORA1HTTKMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL13429070 | 0.81 | ADORA1 (0.47) | ADORA1HTTKMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL13429064 | 0.81 | ADORA1 (0.46) | ADORA1HTTKMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL13429007 | 0.76 | RET (0.42) | ADORA1HTTKMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL13429013 | 0.75 | ADORA1 (0.48) | ADORA1HTTKMT2AALDH1A1SLC6A3 | |
| SCHEMBL13390648 | 0.74 | ADORA1 (0.51) | ADORA1SLC6A3 | |
| SCHEMBL13429003 | 0.74 | RET (0.43) | ADORA1L3MBTL1ALDH1A1 | |
| SCHEMBL13429005 | 0.73 | RET (0.38) | ADORA1HTTKMT2AALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8703934-B2 | Substituted 4-amino-3,5-dicyano-2-thiopyridines and use thereof | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2014-04-22 | — | — | US | disclosed |
| US-20100069363-A1 | SUBSTITUTED 4-AMINO-3,5-DICYANO-2-THIOPYRIDINES AND USE THEREOF | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2010-03-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100069363-A1 | SUBSTITUTED 4-AMINO-3,5-DICYANO-2-THIOPYRIDINES AND USE THEREOF | QDPR, DDC, TPMT | ADORA1 1199/4885HTT 2381/4885KMT2A 1603/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.