Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13456542 | 0.92 | ADORA1 (0.51) | ADORA1SLC6A3 | |
| SCHEMBL13429020 | 0.87 | ADORA1 (0.57) | ADORA1SLC6A3 | |
| SCHEMBL13429014 | 0.86 | ADORA1 (0.55) | ADORA1SLC6A3 | |
| SCHEMBL12910846 | 0.86 | ADORA1 (0.52) | ADORA1SLC6A3 | |
| SCHEMBL12376603 | 0.85 | ADORA1 (0.49) | ADORA1SLC6A3 | |
| SCHEMBL12910794 | 0.84 | ADORA1 (0.59) | ADORA1SLC6A3 | |
| SCHEMBL13429058 | 0.84 | ADORA1 (0.59) | ADORA1SLC6A3 | |
| SCHEMBL13429025 | 0.83 | ADORA1 (0.60) | ADORA1SLC6A3 | |
| SCHEMBL13429107 | 0.82 | ADORA1 (0.55) | ADORA1SLC6A3 | |
| SCHEMBL13429046 | 0.81 | ADORA1 (0.56) | ADORA1SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8703934-B2 | Substituted 4-amino-3,5-dicyano-2-thiopyridines and use thereof | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2014-04-22 | — | — | US | disclosed |
| US-20100069363-A1 | SUBSTITUTED 4-AMINO-3,5-DICYANO-2-THIOPYRIDINES AND USE THEREOF | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2010-03-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100069363-A1 | SUBSTITUTED 4-AMINO-3,5-DICYANO-2-THIOPYRIDINES AND USE THEREOF | QDPR, DDC, TPMT | ADORA1 1199/4885SLC6A3 235/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.