Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 6/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.35 |
| ▸ | HSD11B2 | P80365 | 1/20 | 0.35 |
| ▸ | CES2 | O00748 | 1/20 | 0.33 |
| ▸ | CES1 | P23141 | 1/20 | 0.33 |
| ▸ | CCR1 | P32246 | 3/20 | 0.30 |
| ▸ | CCR2 | P41597 | 3/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 2/20 | 0.30 |
| ▸ | RAB9A | P51151 | 2/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29107877 | 1.00 | EPHX1 (0.35) | EPHX1HSD11B1HSD11B2CES2CES1 | |
| SCHEMBL13433450 | 1.00 | EPHX1 (0.35) | EPHX1HSD11B1HSD11B2CES2CES1 | |
| SCHEMBL29107738 | 1.00 | EPHX1 (0.35) | EPHX1HSD11B1HSD11B2CES2CES1 | |
| SCHEMBL4610992 | 0.95 | EPHX1 (0.35) | EPHX1HSD11B1HSD11B2ALDH1A1MEN1 | |
| SCHEMBL339518 | 0.95 | EPHX1 (0.35) | EPHX1HSD11B1HSD11B2ALDH1A1MEN1 | |
| SCHEMBL7247031 | 0.95 | EPHX1 (0.35) | EPHX1HSD11B1HSD11B2ALDH1A1MEN1 | |
| SCHEMBL23109104 | 0.91 | HSD11B1 (0.35) | EPHX1HSD11B1HSD11B2ALDH1A1MEN1 | |
| SCHEMBL13328489 | 0.91 | HSD11B1 (0.35) | EPHX1HSD11B1HSD11B2ALDH1A1MEN1 | |
| SCHEMBL20614627 | 0.91 | HSD11B1 (0.35) | EPHX1HSD11B1HSD11B2CES2CES1 | |
| SCHEMBL6831574 | 0.84 | MEN1 (0.33) | EPHX1HSD11B1HSD11B2ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010038956-A2 | NOVEL AROMATIC DERIVATIVES AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME | DAEJOO ELECTRONIC MATERIALS CO., LTD. (KR) | 2010-04-08 | — | — | WO | disclosed |