SCHEMBL13434288

SCHEMBL13434288

CONCONc1cccc(C(F)(F)F)c1

nearest known ligand 0.50

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.50
SMN1; SMN2 Q16637 3/20 0.49
MAPT P10636 7/20 0.46
LMNA P02545 4/20 0.46
MAPK1 P28482 1/20 0.46
TP53 P04637 1/20 0.46
GAA P10253 5/20 0.44
MEN1 O00255 3/20 0.44
KMT2A Q03164 3/20 0.44
NPSR1 Q6W5P4 2/20 0.44
XBP1 P17861 1/20 0.44
ALDH1A1 P00352 3/20 0.44
IDH2 P48735 2/20 0.43
RAPGEF4 Q8WZA2 1/20 0.43
TDP1 Q9NUW8 2/20 0.42
HTT P42858 2/20 0.41
RAB9A P51151 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14995940 0.82 L3MBTL1 (0.65) L3MBTL1SMN1; SMN2MAPTLMNAMAPK1
SCHEMBL14155153 0.79 NPC1 (0.46) MAPTGAAMEN1KMT2ANPSR1
SCHEMBL22732110 0.78 L3MBTL1 (0.53) L3MBTL1SMN1; SMN2MAPTLMNAMAPK1
SCHEMBL14155013 0.76 MAPT (0.40) L3MBTL1SMN1; SMN2MAPTLMNAGAA
SCHEMBL14155069 0.76 EGFR (0.35)
SCHEMBL22731816 0.75 KDM4E (0.51) L3MBTL1MAPTLMNAGAAALDH1A1
SCHEMBL31590848 0.75 L3MBTL1 (0.54) L3MBTL1SMN1; SMN2MAPTLMNAMAPK1
SCHEMBL29876277 0.75 L3MBTL1 (0.54) L3MBTL1SMN1; SMN2MAPTLMNAMAPK1
SCHEMBL11406613 0.73 L3MBTL1 (0.53) L3MBTL1SMN1; SMN2MAPTLMNAMAPK1
SCHEMBL14155048 0.73 ALDH1A1 (0.41) L3MBTL1SMN1; SMN2MAPTLMNAMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2010044475-A1 DIP-COATING PROCESS AND METHOD FOR MAKING ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER CANON KABUSHIKI KAISHA (JP) 2010-04-22 WO disclosed
EP-1947515-A2 Electrophotographic photosensitive member, and electrophotgraphic apparatus and process cartridge which make use of the same Canon Kabushiki Kaisha (JP) 2008-07-23 EP disclosed