Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 10/20 | 0.56 |
| ▸ | HTR2C | P28335 | 4/20 | 0.56 |
| ▸ | PDE4A | P27815 | 1/20 | 0.46 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.46 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.46 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.46 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.40 |
| ▸ | HTR2B | P41595 | 3/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | HTR1D | P28221 | 1/20 | 0.39 |
| ▸ | HTR1E | P28566 | 1/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.39 |
| ▸ | HTR7 | P34969 | 1/20 | 0.39 |
| ▸ | HTR6 | P50406 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23094668 | 0.82 | HTR2A (0.45) | HTR2AHTR2CPDE4APDE4BPDE4C | |
| SCHEMBL20756625 | 0.82 | HTR2A (0.62) | HTR2AHTR2CHTR2BHTR1AHTR1D | |
| SCHEMBL2964967 | 0.82 | HSP90AA1 (0.41) | — | |
| SCHEMBL21490281 | 0.78 | HSP90AA1 (0.40) | — | |
| SCHEMBL21823013 | 0.77 | HTR2A (0.44) | HTR2AHTR2CPDE4APDE4BPDE4C | |
| SCHEMBL14399505 | 0.76 | HTR2A (0.57) | HTR2AHTR2CHTR2BHTR1AHTR1D | |
| SCHEMBL1992428 | 0.74 | EPHX2 (0.58) | EPHX2ALDH1A1 | |
| SCHEMBL8021476 | 0.74 | S1PR1 (0.52) | HTR2AHTR2CPDE4APDE4BPDE4C | |
| SCHEMBL130004 | 0.73 | CETP (0.45) | — | |
| SCHEMBL5371918 | 0.73 | AR (0.54) | HTR2AHTR2CS1PR1CYP3A4AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7700366-B2 | Fluorescent, semi-conductive polymers, and devices comprising them | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2010-04-20 | — | — | US | disclosed |