Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.41 |
| ▸ | KIF11 | P52732 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 3/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.34 |
| ▸ | POLQ | O75417 | 4/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 3/20 | 0.33 |
| ▸ | CES2 | O00748 | 2/20 | 0.31 |
| ▸ | KLF10 | Q13118 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.31 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.31 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.31 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.31 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21490281 | 0.95 | HSP90AA1 (0.40) | HSP90AA1HSP90AB1KIF11IDO1TRPV1 | |
| SCHEMBL13434366 | 0.82 | HTR2A (0.56) | — | |
| SCHEMBL2961793 | 0.82 | HSP90AA1 (0.34) | HSP90AA1HSP90AB1KIF11 | |
| SCHEMBL3873033 | 0.80 | KIF11 (0.47) | HSP90AA1HSP90AB1KIF11IDO1TRPV1 | |
| SCHEMBL19491471 | 0.80 | KIF11 (0.40) | HSP90AA1HSP90AB1KIF11IDO1POLQ | |
| SCHEMBL695215 | 0.79 | IDO1 (0.43) | HSP90AA1HSP90AB1KIF11IDO1NOTUM | |
| SCHEMBL21490279 | 0.79 | KIF11 (0.34) | HSP90AA1HSP90AB1KIF11TRPV1 | |
| SCHEMBL1993639 | 0.79 | CES2 (0.52) | IDO1POLQCES2 | |
| SCHEMBL3278241 | 0.79 | IDO1 (0.61) | KIF11IDO1POLQSLC6A2SLC6A4 | |
| SCHEMBL2297172 | 0.79 | KIF11 (0.39) | HSP90AA1HSP90AB1KIF11IDO1POLQ |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8298830-B2 | Organic materials able to detect analytes | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2012-10-30 | — | — | US | disclosed |
| US-20100310424-A1 | ORGANIC MATERIALS ABLE TO DETECT ANALYTES | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2010-12-09 | — | — | US | disclosed |
| US-7759127-B2 | Organic materials able to detect analytes | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2010-07-20 | — | — | US | disclosed |
| US-7700366-B2 | Fluorescent, semi-conductive polymers, and devices comprising them | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2010-04-20 | — | — | US | disclosed |
| US-7700366-B2 | Fluorescent, semi-conductive polymers, and devices comprising them | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2010-04-20 | — | — | US | disclosed |
| US-20060073607-A1 | Organic materials able to detect analytes | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2006-04-06 | — | — | US | disclosed |
| US-20050196775-A1 | Fluorescent, semi-conductive polymers, and devices comprising them | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2005-09-08 | — | — | US | disclosed |