Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 11/20 | 0.39 |
| ▸ | DCUN1D1 | Q96GG9 | 2/20 | 0.36 |
| ▸ | HTR7 | P34969 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | TYMS | P04818 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12460243 | 0.83 | PDK2 (0.59) | PDK2 | |
| SCHEMBL7465746 | 0.67 | KDM4E (0.57) | DCUN1D1KDM4EALDH1A1NPC1RAB9A | |
| SCHEMBL30341830 | 0.67 | PDK2 (0.52) | PDK2ALDH1A1TSHR | |
| SCHEMBL2239449 | 0.67 | PDK2 (0.52) | PDK2ALDH1A1TSHR | |
| SCHEMBL2629349 | 0.63 | NR1H2 (0.61) | DCUN1D1HTR7KDM4ECYP1A2ADORA2A | |
| SCHEMBL28613659 | 0.62 | HTR7 (0.49) | PDK2HTR7HTR2BCYP1A2ALDH1A1 | |
| SCHEMBL17279734 | 0.61 | DCUN1D1 (0.46) | DCUN1D1KDM4ECYP1A2ADORA2AALDH1A1 | |
| SCHEMBL12588208 | 0.61 | MAOA (0.49) | PDK2TYMSCYP1A2CYP2C19ALDH1A1 | |
| SCHEMBL11482321 | 0.60 | MEN1 (0.48) | PDK2KDM4ECYP1A2CYP3A4ALDH1A1 | |
| SCHEMBL18386029 | 0.60 | PDK2 (0.46) | PDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010041748-A1 | FLUORENE COMPOUND AND USE THEREOF FOR MEDICAL PURPOSES | 日本たばこ産業株式会社 (JP) | 2010-04-15 | — | — | WO | disclosed |