Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 2/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | TP53 | P04637 | 3/20 | 0.51 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 7/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19659608 | 0.98 | THRB (0.66) | THRBALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL14475296 | 0.93 | ALDH1A1 (0.58) | THRBALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL21776081 | 0.93 | ALDH1A1 (0.58) | THRBALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL15082554 | 0.93 | THRB (0.72) | THRBALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL14764557 | 0.93 | THRB (0.62) | THRBALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL39816 | 0.92 | THRB (0.74) | THRBALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL23169982 | 0.90 | THRB (0.56) | THRBALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL12777842 | 0.88 | ALDH1A1 (0.64) | THRBALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL22108772 | 0.87 | ALDH1A1 (0.71) | THRBALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL21776175 | 0.87 | ALDH1A1 (0.71) | THRBALDH1A1TP53HIF1ACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8574454-B2 | Patternable liquid crystal polymer comprising thio-ether units | ROLIC AG (CH) | 2013-11-05 | — | — | US | disclosed |
| US-20100059709-A1 | PATTERNABLE LIQUID CRYSTAL POLYMER COMPRISING THIO-ETHER UNITS | ROLIC AG (CH) | 2010-03-11 | — | — | US | disclosed |