SCHEMBL13435235

SCHEMBL13435235

CCC(=O)NCc1cn(C)nn1

nearest known ligand 0.41

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
GLS O94925 1/20 0.41
KCNJ1 P48048 2/20 0.41
KDM4E B2RXH2 1/20 0.40
LMNA P02545 1/20 0.40
RAB9A P51151 1/20 0.40
BRD4 O60885 1/20 0.39
BRD2 P25440 1/20 0.39
NOTUM Q6P988 1/20 0.38
POLB P06746 1/20 0.36
GBA1 P04062 6/20 0.36
MIF P14174 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13435285 0.85 KCNJ1 (0.40) KCNJ1BRD4BRD2NOTUMMIF
SCHEMBL21424267 0.83 EPHX2 (0.48) GBA1
SCHEMBL17133298 0.83 MALT1 (0.43) KCNJ1LMNABRD4BRD2NOTUM
SCHEMBL17369045 0.82 GLS (0.45) GLSKDM4ELMNARAB9AGBA1
SCHEMBL15336482 0.81 KCNJ1 (0.41) KCNJ1BRD4BRD2NOTUMMIF
SCHEMBL9891847 0.80 GLS (0.41) GLSKDM4ELMNARAB9ANOTUM
SCHEMBL20997046 0.80 PARP14 (0.41) GLSKDM4ELMNARAB9ANOTUM
SCHEMBL22917015 0.79 KCNJ1 (0.40) KCNJ1
SCHEMBL13872481 0.79 KCNJ1 (0.56) KCNJ1KDM4ELMNARAB9ABRD4
SCHEMBL25123070 0.78 GLS (0.48) GLSGBA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240226343-A1 NEUROPEPTIDE Y1 RECEPTOR (NPY1R) TARGETED THERAPEUTICS AND USES THEREOF RADIONETICS ONCOLOGY, INC. 2024-07-11 US disclosed
WO-2024112612-A1 NEUROPEPTIDE Y1 RECEPTOR (NPY1R) TARGETED THERAPEUTICS AND USES THEREOF RADIONETICS ONCOLOGY, INC. (US) 2024-05-30 WO disclosed
US-20100069607-A1 METHOD OF COVALENTLY LINKING A CARBOHYDRATE OR POLYALKYLENE OXIDE TO A PEPTIDE, PRECURSORS FOR USE IN THE METHOD AND RESULTANT PRODUCTS UCL BUSINESS PLC (GB) 2010-03-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100069607-A1 METHOD OF COVALENTLY LINKING A CARBOHYDRATE OR POLYALKYLENE OXIDE TO A PEPTIDE, PRECURSORS FOR USE IN THE METHOD AND RESULTANT PRODUCTS MSR1, C9, ADM2 GLS 2827/4885KCNJ1 3366/4885KDM4E 2266/4885
US-20240226343-A1 NEUROPEPTIDE Y1 RECEPTOR (NPY1R) TARGETED THERAPEUTICS AND USES THEREOF NPY1R, NPY2R, NPY4R GLS 1411/4885KCNJ1 4767/4885KDM4E 3543/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.