Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLS | O94925 | 2/20 | 0.41 |
| ▸ | CA12 | O43570 | 2/20 | 0.37 |
| ▸ | CA1 | P00915 | 2/20 | 0.37 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | CA9 | Q16790 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | MIF | P14174 | 3/20 | 0.34 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24095996 | 0.84 | EPHX2 (0.47) | — | |
| SCHEMBL9889152 | 0.83 | MAPT (0.39) | CA12CA1CA2CA9NOTUM | |
| SCHEMBL25138435 | 0.82 | RIPK1 (0.47) | CA12CA1CA2CA9RAB9A | |
| SCHEMBL13435235 | 0.80 | GLS (0.41) | GLSKDM4ELMNARAB9ANOTUM | |
| SCHEMBL17369045 | 0.78 | GLS (0.45) | GLSKDM4ELMNARAB9AFTO | |
| SCHEMBL19497747 | 0.77 | MAP3K8 (0.34) | CA12CA1CA2CA9 | |
| SCHEMBL20997046 | 0.76 | PARP14 (0.41) | GLSKDM4ELMNARAB9ANOTUM | |
| SCHEMBL21790462 | 0.75 | KDM4E (0.38) | GLSKDM4ELMNARAB9ANOTUM | |
| SCHEMBL21672550 | 0.75 | MAP3K8 (0.36) | KDM4E | |
| SCHEMBL25446419 | 0.74 | SMN1; SMN2 (0.39) | CA1CA2KDM4ELMNARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120142711-A1 | ACID-LABILE TRIGGER UNITS | KTB TUMORFORSCHUNGSGESELLSCHAFT MBH (DE) | 2012-06-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120142711-A1 | ACID-LABILE TRIGGER UNITS | ASIC1, ABL1, CA9 | GLS 4631/4885CA12 13/4885CA1 8/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.