Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.46 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.42 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30069487 | 0.95 | TDP1 (0.69) | TDP1ALDH1A1KDM4ESMN1; SMN2LMNA | |
| SCHEMBL19557489 | 0.93 | TDP1 (0.57) | TDP1ALDH1A1KDM4ESMN1; SMN2LMNA | |
| SCHEMBL13230077 | 0.89 | TDP1 (0.61) | TDP1ALDH1A1KDM4ESMN1; SMN2LMNA | |
| SCHEMBL13435254 | 0.87 | TDP1 (0.51) | TDP1ALDH1A1KDM4ESMN1; SMN2LMNA | |
| SCHEMBL14654334 | 0.86 | TDP1 (0.59) | TDP1ALDH1A1KDM4ESMN1; SMN2KMT2A | |
| SCHEMBL14654314 | 0.85 | TDP1 (0.57) | TDP1ALDH1A1KDM4ESMN1; SMN2LMNA | |
| SCHEMBL16855860 | 0.84 | TDP1 (0.56) | TDP1ALDH1A1KDM4ESMN1; SMN2LMNA | |
| SCHEMBL23029083 | 0.83 | TDP1 (0.55) | TDP1ALDH1A1LMNAKMT2AMTNR1A | |
| SCHEMBL10378725 | 0.83 | TDP1 (0.57) | TDP1ALDH1A1KDM4ESMN1; SMN2LMNA | |
| SCHEMBL16982683 | 0.83 | TDP1 (0.52) | TDP1ALDH1A1SMN1; SMN2KMT2AMTNR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100068748-A1 | Fluorescent Ion Indicators for Cadmium and Lanthanide Ion Detection | INVITROGEN CORPORATION (US) | 2010-03-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100068748-A1 | Fluorescent Ion Indicators for Cadmium and Lanthanide Ion Detection | SLC30A6, SLC39A14, SLC39A7 | TDP1 3745/4885ALDH1A1 1607/4885KDM4E 3136/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.