Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.50 |
| ▸ | MAPT | P10636 | 8/20 | 0.50 |
| ▸ | HPGD | P15428 | 5/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | FDPS | P14324 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19557490 | 0.90 | ALDH1A1 (0.44) | TDP1ALDH1A1MAPTHPGDCYP2C9 | |
| SCHEMBL13230081 | 0.89 | ALDH1A1 (0.48) | TDP1ALDH1A1MAPTHPGDCYP2C9 | |
| SCHEMBL24189141 | 0.87 | FDPS (0.47) | TDP1ALDH1A1MAPTHPGDCYP2C9 | |
| SCHEMBL13435255 | 0.87 | TDP1 (0.64) | TDP1ALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL10123080 | 0.85 | LMNA (0.48) | TDP1ALDH1A1MAPTHPGDCYP2C9 | |
| SCHEMBL30069487 | 0.83 | TDP1 (0.69) | TDP1ALDH1A1MAPTHPGDSMN1; SMN2 | |
| SCHEMBL14654334 | 0.82 | TDP1 (0.59) | TDP1ALDH1A1MAPTSMN1; SMN2NPSR1 | |
| SCHEMBL19557489 | 0.81 | TDP1 (0.57) | TDP1ALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL14654314 | 0.81 | TDP1 (0.57) | TDP1ALDH1A1MAPTHPGDCYP2C9 | |
| SCHEMBL19773378 | 0.81 | TDP1 (0.52) | TDP1ALDH1A1MAPTHPGDCYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100068748-A1 | Fluorescent Ion Indicators for Cadmium and Lanthanide Ion Detection | INVITROGEN CORPORATION (US) | 2010-03-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100068748-A1 | Fluorescent Ion Indicators for Cadmium and Lanthanide Ion Detection | SLC30A6, SLC39A14, SLC39A7 | TDP1 3745/4885ALDH1A1 1607/4885MAPT 3860/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.