Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.41 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.39 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.37 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13435255 | 0.93 | TDP1 (0.64) | TDP1ALDH1A1KDM4ESMN1; SMN2LMNA | |
| SCHEMBL30069487 | 0.89 | TDP1 (0.69) | TDP1ALDH1A1KDM4ESMN1; SMN2LMNA | |
| SCHEMBL31344167 | 0.83 | TDP1 (0.78) | TDP1ALDH1A1KDM4ESMN1; SMN2LMNA | |
| SCHEMBL17707465 | 0.83 | TDP1 (0.78) | TDP1ALDH1A1KDM4ESMN1; SMN2LMNA | |
| SCHEMBL13230077 | 0.83 | TDP1 (0.61) | TDP1ALDH1A1KDM4ESMN1; SMN2LMNA | |
| SCHEMBL19557490 | 0.83 | ALDH1A1 (0.44) | TDP1ALDH1A1SMN1; SMN2LMNAKMT2A | |
| SCHEMBL13435254 | 0.81 | TDP1 (0.51) | TDP1ALDH1A1KDM4ESMN1; SMN2LMNA | |
| SCHEMBL19557494 | 0.81 | ALDH1A1 (0.38) | TDP1ALDH1A1KDM4ESMN1; SMN2LMNA | |
| SCHEMBL14654334 | 0.81 | TDP1 (0.59) | TDP1ALDH1A1KDM4ESMN1; SMN2KMT2A | |
| SCHEMBL14654314 | 0.80 | TDP1 (0.57) | TDP1ALDH1A1KDM4ESMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9810700-B1 | Fluorogenic calcium ion indicators and methods of using the same | AAT BIOQUEST, INC. (US) | 2017-11-07 | — | — | US | disclosed |
| US-9810700-B1 | Fluorogenic calcium ion indicators and methods of using the same | AAT BIOQUEST, INC. (US) | 2017-11-07 | — | — | US | disclosed |