Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA3 | P22001 | 9/20 | 0.59 |
| ▸ | CCR1 | P32246 | 8/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | TET3 | O43151 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | FBXL19 | Q6PCT2 | 1/20 | 0.50 |
| ▸ | CXXC5 | Q7LFL8 | 1/20 | 0.50 |
| ▸ | TET1 | Q8NFU7 | 1/20 | 0.50 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.50 |
| ▸ | CXXC4 | Q9H2H0 | 1/20 | 0.50 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.50 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12265188 | 0.83 | KCNA3 (0.59) | KCNA3CCR1RAB9ANPSR1OPRM1 | |
| SCHEMBL12313132 | 0.79 | KCNA3 (0.56) | KCNA3CCR1RAB9ANPSR1OPRM1 | |
| SCHEMBL2525815 | 0.78 | OPRM1 (0.57) | RAB9ANPSR1TET3KMT2AFBXL19 | |
| SCHEMBL27645407 | 0.78 | KMT2A (0.55) | TET3KMT2AFBXL19CXXC5TET1 | |
| SCHEMBL12216179 | 0.76 | KMT2A (0.54) | KCNA3RAB9ANPSR1TET3KMT2A | |
| SCHEMBL12313089 | 0.76 | KCNA3 (0.55) | KCNA3CCR1RAB9ANPSR1OPRM1 | |
| SCHEMBL12265183 | 0.75 | KCNA3 (0.73) | KCNA3CCR1RAB9ANPSR1OPRM1 | |
| SCHEMBL2529201 | 0.75 | KMT2A (0.57) | TET3KMT2AFBXL19CXXC5TET1 | |
| SCHEMBL11601787 | 0.75 | KCNA3 (1.00) | KCNA3CCR1 | |
| SCHEMBL12313133 | 0.75 | KCNA3 (0.56) | KCNA3CCR1RAB9ANPSR1OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7687518-B2 | Therapeutic agents useful for treating pain | PURDUE PHARMA L.P. (US) | 2010-03-30 | — | — | US | disclosed |
| US-7687518-B2 | Therapeutic agents useful for treating pain | PURDUE PHARMA L.P. (US) | 2010-03-30 | — | — | US | disclosed |
| EP-1562932-B9 | 4-TETRAZOLYL-4-PHENYLPIPERIDINE DERIVATIVES FOR TREATING PAIN | EURO CELTIQUE SA (LU) | 2007-09-12 | — | — | EP | disclosed |
| US-7202259-B2 | Therapeutic agents useful for treating pain | EURO-CELTIQUE S.A. (LU) | 2007-04-10 | — | — | US | disclosed |
| US-7202259-B2 | Therapeutic agents useful for treating pain | EURO-CELTIQUE S.A. (LU) | 2007-04-10 | — | — | US | disclosed |
| EP-1562932-B1 | 4-TETRAZOLYL-4-PHENYLPIPERIDINE DERIVATIVES FOR TREATING PAIN | EURO CELTIQUE SA (LU) | 2007-04-04 | — | — | EP | disclosed |