Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CTSL | P07711 | 1/20 | 0.38 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.38 |
| ▸ | SYK | P43405 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24998912 | 0.83 | TACR1 (0.38) | HTTNPC1RAB9ASMN1; SMN2CTSL | |
| SCHEMBL10698128 | 0.78 | HTR2C (0.43) | HTTPOLBNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL20323978 | 0.76 | HTR2C (0.45) | HTTNPC1RAB9ASMN1; SMN2CTSL | |
| SCHEMBL5491000 | 0.75 | SMN1; SMN2 (0.43) | POLBNPC1RAB9ASMN1; SMN2HTR2C | |
| SCHEMBL3005761 | 0.75 | CTSL (0.39) | CTSLHTR2C | |
| SCHEMBL3005759 | 0.75 | CTSL (0.39) | CTSLHTR2C | |
| SCHEMBL15114609 | 0.75 | CTSL (0.39) | CTSLHTR2C | |
| SCHEMBL30882363 | 0.73 | JAK2 (0.39) | — | |
| SCHEMBL30089180 | 0.73 | TACR1 (0.40) | HTTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL24175974 | 0.73 | TACR1 (0.40) | HTTNPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100056432-A1 | TEMPLATE-FIXED PEPTIDOMIMETICS WITH ANTIBACTERIAL ACTIVITY | POLYPHOR LTD. (CH) | 2010-03-04 | — | — | US | disclosed |
| US-7253146-B2 | Template-fixed peptidomimetics with antimicrobial activity | POLYPHOR LTD (CH) | 2007-08-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100056432-A1 | TEMPLATE-FIXED PEPTIDOMIMETICS WITH ANTIBACTERIAL ACTIVITY | POLL, QPCTL, PEPD | HTT 1703/4885POLB 58/4885NPC1 4759/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.