Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 2/20 | 0.52 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.51 |
| ▸ | PIK3CA | P42336 | 4/20 | 0.50 |
| ▸ | CNR2 | P34972 | 3/20 | 0.50 |
| ▸ | DGAT1 | O75907 | 3/20 | 0.49 |
| ▸ | ATR | Q13535 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14097709 | 0.77 | PIK3CA (0.53) | HDAC6PIK3CACNR2 | |
| SCHEMBL2244482 | 0.75 | HDAC6 (0.61) | FAAHHDAC6PIK3CACNR2NPC1 | |
| SCHEMBL13436779 | 0.75 | FAAH (0.56) | FAAHHDAC6DGAT1NPC1ALDH1A1 | |
| SCHEMBL3476250 | 0.74 | FAAH (0.61) | FAAHHDAC6DGAT1NPC1ALDH1A1 | |
| SCHEMBL12928163 | 0.74 | PIK3CA (0.70) | PIK3CADGAT1 | |
| SCHEMBL16773016 | 0.74 | CNR2 (0.69) | CNR2DGAT1ATRALDH1A1GAA | |
| SCHEMBL3474807 | 0.74 | FAAH (0.60) | FAAHHDAC6DGAT1NPC1ALDH1A1 | |
| SCHEMBL3475760 | 0.74 | FAAH (0.60) | FAAHHDAC6DGAT1NPC1ALDH1A1 | |
| SCHEMBL3475438 | 0.73 | FAAH (0.57) | FAAHHDAC6DGAT1NPC1ALDH1A1 | |
| SCHEMBL3478425 | 0.73 | FAAH (0.57) | FAAHHDAC6DGAT1NPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010039186-A2 | COMPOUNDS USEFUL AS FAAH MODULATORS AND USES THEREOF | RENOVIS, INC. (US) | 2010-04-08 | — | — | WO | disclosed |