Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 8/20 | 0.71 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.56 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.53 |
| ▸ | ELANE | P08246 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | SSTR5 | P35346 | 2/20 | 0.39 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.37 |
| ▸ | HRH1 | P35367 | 1/20 | 0.37 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13436763 | 0.89 | FAAH (0.76) | FAAHHDAC6PIK3CAELANESSTR5 | |
| SCHEMBL3475819 | 0.85 | FAAH (0.65) | FAAHHDAC6PIK3CAELANENPC1 | |
| SCHEMBL3476570 | 0.83 | FAAH (1.00) | FAAHHDAC6PIK3CAELANENPC1 | |
| SCHEMBL13436720 | 0.83 | FAAH (0.78) | FAAHHDAC6PIK3CASMN1; SMN2SSTR5 | |
| SCHEMBL3477307 | 0.82 | FAAH (0.66) | FAAHHDAC6PIK3CAELANE | |
| SCHEMBL3477409 | 0.81 | FAAH (0.71) | FAAHHDAC6PIK3CAELANENPC1 | |
| SCHEMBL3477717 | 0.81 | HDAC6 (0.67) | FAAHHDAC6PIK3CAELANESSTR5 | |
| SCHEMBL3477428 | 0.80 | FAAH (0.64) | FAAHHDAC6PIK3CAELANEAAK1 | |
| SCHEMBL3474618 | 0.79 | FAAH (0.62) | FAAHHDAC6PIK3CAELANEALDH1A1 | |
| SCHEMBL3476251 | 0.78 | FAAH (0.60) | FAAHHDAC6PIK3CAELANESSTR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010039186-A2 | COMPOUNDS USEFUL AS FAAH MODULATORS AND USES THEREOF | RENOVIS, INC. (US) | 2010-04-08 | — | — | WO | disclosed |