Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 8/20 | 0.66 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.60 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.58 |
| ▸ | ELANE | P08246 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.46 |
| ▸ | PDE5A | O76074 | 1/20 | 0.44 |
| ▸ | ACP1 | P24666 | 1/20 | 0.44 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.44 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3477409 | 0.88 | FAAH (0.71) | FAAHPIK3CAHDAC6ELANEGAA | |
| SCHEMBL3475819 | 0.88 | FAAH (0.65) | FAAHPIK3CAHDAC6ELANE | |
| SCHEMBL13436763 | 0.85 | FAAH (0.76) | FAAHPIK3CAHDAC6ELANEMAPT | |
| SCHEMBL3477428 | 0.85 | FAAH (0.64) | FAAHPIK3CAHDAC6ELANE | |
| SCHEMBL3475989 | 0.85 | FAAH (0.60) | FAAHPIK3CAHDAC6ELANE | |
| SCHEMBL3477061 | 0.85 | FAAH (0.58) | FAAHPIK3CAHDAC6ELANEMAPT | |
| SCHEMBL3475774 | 0.84 | FAAH (0.61) | FAAHPIK3CAHDAC6ELANEMAPT | |
| SCHEMBL3474618 | 0.84 | FAAH (0.62) | FAAHPIK3CAHDAC6ELANE | |
| SCHEMBL3475416 | 0.83 | FAAH (0.61) | FAAHPIK3CAHDAC6ELANE | |
| SCHEMBL3477717 | 0.83 | HDAC6 (0.67) | FAAHPIK3CAHDAC6ELANEDGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010039186-A2 | COMPOUNDS USEFUL AS FAAH MODULATORS AND USES THEREOF | RENOVIS, INC. (US) | 2010-04-08 | — | — | WO | disclosed |
| WO-2010039186-A2 | COMPOUNDS USEFUL AS FAAH MODULATORS AND USES THEREOF | RENOVIS, INC. (US) | 2010-04-08 | — | — | WO | disclosed |