SCHEMBL1343771

SCHEMBL1343771

CCCCCCCc1ccccc1CCCCCCC

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LIPG Q9Y5X9 1/20 0.69
NR1H2 P55055 1/20 0.55
NR1H3 Q13133 1/20 0.55
KCNH2 Q12809 2/20 0.52
BID P55957 3/20 0.52
MCL1 Q07820 3/20 0.52
BCL2L1 Q07817 2/20 0.52
BAK1 Q16611 2/20 0.52
KAT8 Q9H7Z6 2/20 0.52
PPARG P37231 1/20 0.52
PPARA Q07869 1/20 0.52
EP300 Q09472 1/20 0.52
KAT2A Q92830 1/20 0.52
KAT2B Q92831 1/20 0.52
KAT5 Q92993 1/20 0.52
SAE1 Q9UBE0 1/20 0.52
ALOX5 P09917 2/20 0.50
THRA P10827 1/20 0.50
THRB P10828 1/20 0.50
PTGS2 P35354 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10755599 1.00 LIPG (0.69) LIPGNR1H2NR1H3KCNH2BID
SCHEMBL7534048 1.00 LIPG (0.69) LIPGNR1H2NR1H3KCNH2BID
SCHEMBL7516668 1.00 LIPG (0.69) LIPGNR1H2NR1H3KCNH2BID
SCHEMBL10980560 1.00 LIPG (0.69) LIPGNR1H2NR1H3KCNH2BID
SCHEMBL6679764 1.00 LIPG (0.69) LIPGNR1H2NR1H3KCNH2BID
SCHEMBL2511612 1.00 LIPG (0.69) LIPGNR1H2NR1H3KCNH2BID
SCHEMBL15809821 1.00 LIPG (0.69) LIPGNR1H2NR1H3KCNH2BID
SCHEMBL9699968 1.00 LIPG (0.69) LIPGNR1H2NR1H3KCNH2BID
SCHEMBL18496530 1.00 LIPG (0.69) LIPGNR1H2NR1H3KCNH2BID
SCHEMBL1412738 1.00 LIPG (0.69) LIPGNR1H2NR1H3KCNH2BID

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2989070-B1 IMPROVED FULLERENE DERIVATIVES AND RELATED MATERIALS, METHODS AND DEVICES MERCK PATENT GMBH (DE) 2019-08-14 EP disclosed
US-10361371-B2 Fullerene derivatives, and related materials, methods and devices NANO-C, INC. (US) 2019-07-23 US disclosed
US-10361371-B2 Fullerene derivatives, and related materials, methods and devices NANO-C, INC. (US) 2019-07-23 US disclosed
EP-1950279-B1 REFRIGERATOR IDEMITSU KOSAN CO (JP) 2018-08-08 EP disclosed
CN-105121393-B Improved fullerene derivatives and related materials, methods and devices 默克专利有限公司 2018-06-15 CN disclosed
CN-104470890-B Aminoethylation process for preparing aryloxyalkylene amine compounds 雪佛龙奥伦耐有限责任公司 2017-09-26 CN disclosed
US-20170098775-A1 FULLERENE DERIVATIVES, AND RELATED MATERIALS, METHODS AND DEVICES NANO-C, INC. 2017-04-06 US disclosed
US-20170098775-A1 FULLERENE DERIVATIVES, AND RELATED MATERIALS, METHODS AND DEVICES NANO-C, INC. 2017-04-06 US disclosed
CN-103168063-B Conjugated polymers 默克专利股份有限公司 2016-11-23 CN disclosed
US-9502658-B2 Fullerene derivatives and related materials, methods, and devices NANO-C, INC. (US) 2016-11-22 US disclosed
US-20090159836-A1 REFRIGERATOR OIL IDEMITSU KOSAN CO., LTD. (JP) 2009-06-25 US disclosed
CN-101305083-A Refrigerating machine oil IDEMITSU KOSAN CO (JP) 2008-11-12 CN disclosed
EP-1950279-A1 REFRIGERATOR OIL Idemitsu Kosan Co., Ltd. (JP) 2008-07-30 EP disclosed
EP-0985649-B1 Method for producing an aromatic compound having an alkyl group with at least three carbon atoms TORAY INDUSTRIES (JP) 2004-11-24 EP disclosed
US-6462248-B1 THROUGH CONVERSION, ISOMERIZATION AND/OR ADSORPTIVE SEPARATION OF AROMATIC COMPOUNDS TORAY INDUSTRIES, INC. (JP) 2002-10-08 US disclosed
EP-0985649-A2 Method for producing an aromatic compound having an alkyl group with at least three carbon atoms TORAY INDUSTRIES, INC. (JP) 2000-03-15 EP disclosed
WO-1998010033-A1 SOLVENT FOR SOLID CRUDE OIL DEPOSITS DESTINY OIL ANSTALT (LI) 1998-03-12 WO disclosed
US-4599445-A Process for benzophenone tetracarboxylic acid THE DOW CHEMICAL COMPANY (US) 1986-07-08 US disclosed
US-4562271-A Preparation of 3-alkanoyloxyphthalides THE UPJOHN COMPANY (US) 1985-12-31 US disclosed
US-4485247-A 3-Alkanoyloxyphthalides THE UPJOHN COMPANY (US) 1984-11-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10361371-B2 Fullerene derivatives, and related materials, methods and devices PPOX, OCIAD2, OCIAD1 LIPG 2265/4885NR1H2 2909/4885NR1H3 2832/4885
US-20170098775-A1 FULLERENE DERIVATIVES, AND RELATED MATERIALS, METHODS AND DEVICES PPOX, OCIAD2, OCIAD1 LIPG 2265/4885NR1H2 2909/4885NR1H3 2832/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.