SCHEMBL134379

SCHEMBL134379

C[C@H](CCC(=O)O[C@]1(C)CCOC(=O)C1)[C@H]1CC[C@H]2[C@@H]3CC[C@@H]4C[C@H](O)CC[C@]4(C)[C@H]3CC[C@]12C

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPBAR1 Q8TDU6 5/20 0.68
VDR P11473 5/20 0.68
HIF1A Q16665 3/20 0.68
CYP2C9 P11712 2/20 0.68
EPHA2 P29317 5/20 0.63
CASP7 P55210 3/20 0.63
TP53 P04637 2/20 0.63
MAPK1 P28482 2/20 0.63
HSD17B10 Q99714 2/20 0.63
BLM P54132 2/20 0.63
TDP1 Q9NUW8 2/20 0.63
USP2 O75604 2/20 0.63
CYP3A4 P08684 2/20 0.63
MDM4 O15151 1/20 0.63
MAPT P10636 1/20 0.63
HSPD1 P10809 1/20 0.63
TSHR P16473 1/20 0.63
PTPN2 P17706 1/20 0.63
PTPN1 P18031 1/20 0.63
BRCA1 P38398 1/20 0.63

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL134380 1.00 GPBAR1 (0.68) GPBAR1VDRHIF1ACYP2C9EPHA2
SCHEMBL445628 1.00 GPBAR1 (0.68) GPBAR1VDRHIF1ACYP2C9EPHA2
SCHEMBL446309 0.91 MAPT (0.70) GPBAR1VDRHIF1ACYP2C9MAPK1
SCHEMBL136045 0.91 MAPT (0.70) GPBAR1VDRHIF1ACYP2C9MAPK1
SCHEMBL13427015 0.89 GPBAR1 (0.68) GPBAR1TDP1CYP3A4NR1H4LMNA
SCHEMBL20962050 0.89 GPBAR1 (0.68) GPBAR1TDP1CYP3A4NR1H4LMNA
SCHEMBL132512 0.89 GPBAR1 (0.68) GPBAR1TDP1CYP3A4NR1H4LMNA
SCHEMBL15436244 0.87 GPBAR1 (0.55) GPBAR1VDRHIF1ACYP2C9TDP1
Lithocholic Acid SCHEMBL5437324 0.82 GPBAR1 (0.78) GPBAR1VDRHIF1ACYP2C9EPHA2
Lithocholic Acid SCHEMBL5437327 0.82 GPBAR1 (0.78) GPBAR1VDRHIF1ACYP2C9EPHA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 168 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11681222-B2 Fluorine-containing polymer, purification method, and radiation-sensitive resin composition JSR CORPORATION (JP) 2023-06-20 US disclosed
US-20220137508-A9 FLUORINE-CONTAINING POLYMER, PURIFICATION METHOD, AND RADIATION-SENSITIVE RESIN COMPOSITION JSR CORPORATION (JP) 2022-05-05 US disclosed
US-20210278764-A1 FLUORINE-CONTAINING POLYMER, PURIFICATION METHOD, AND RADIATION-SENSITIVE RESIN COMPOSITION JSR CORPORATION (JP) 2021-09-09 US disclosed
US-11036133-B2 Fluorine-containing polymer, purification method, and radiation-sensitive resin composition JSR CORPORATION (JP) 2021-06-15 US disclosed
US-20200124961-A1 FLUORINE-CONTAINING POLYMER, PURIFICATION METHOD, AND RADIATION-SENSITIVE RESIN COMPOSITION JSR CORPORATION (JP) 2020-04-23 US disclosed
US-10620534-B2 Fluorine-containing polymer, purification method, and radiation-sensitive resin composition JSR CORPORATION (JP) 2020-04-14 US disclosed
US-20190278175-A9 FLUORINE-CONTAINING POLYMER, PURIFICATION METHOD, AND RADIATION-SENSITIVE RESIN COMPOSITION JSR CORPORATION (JP) 2019-09-12 US disclosed
US-20190025695-A1 FLUORINE-CONTAINING POLYMER, PURIFICATION METHOD, AND RADIATION-SENSITIVE RESIN COMPOSITION JSR CORPORATION (JP) 2019-01-24 US disclosed
US-10082733-B2 Fluorine-containing polymer, purification method, and radiation-sensitive resin composition JSR CORPORATION (JP) 2018-09-25 US disclosed
EP-2325695-B1 RADIATION-SENSITIVE RESIN COMPOSITION JSR CORP (JP) 2017-12-20 EP disclosed
EP-1225480-A2 Radiation-sensitive resin composition JSR Corporation (JP) 2002-07-24 EP disclosed
US-20020009668-A1 Radiation-sensitive resin composition JSR CORPORATION (JP) 2002-01-24 US disclosed
US-20020009667-A1 Radiation-sensitive resin composition JSR CORPORATION (JP) 2002-01-24 US disclosed
EP-1164434-A2 Radiation-sensitive resin composition JSR Corporation (JP) 2001-12-19 EP disclosed
EP-1162506-A1 Radiation-sensitive resin composition JSR Corporation (JP) 2001-12-12 EP disclosed
US-20010023050-A1 Radiation-sensitive resin composition JSR CORPORATION (JP) 2001-09-20 US disclosed
EP-1122605-A2 Radiation-sensitive resin composition JSR Corporation (JP) 2001-08-08 EP disclosed
EP-1085379-A1 Radiation-sensitive resin composition JSR Corporation (JP) 2001-03-21 EP disclosed
US-6180316-B1 SUITABLE FOR USE AS CHEMICALLY AMPLIFIED RESIST USED IN MANUFACTURING OF INTEGRATED CIRCUITS JSR CORPORATION (JP) 2001-01-30 US disclosed
EP-0930541-A1 Radiation sensitive resin composition JSR Corporation (JP) 1999-07-21 EP disclosed