SCHEMBL446309

SCHEMBL446309

C[C@H](CCC(=O)OC1(C)CCOC(=O)C1)[C@H]1CC[C@H]2[C@@H]3CC[C@@H]4C[C@H](O)CC[C@]4(C)[C@H]3C[C@H](O)[C@]12C

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.70
MEN1 O00255 2/20 0.70
KMT2A Q03164 2/20 0.70
USP2 O75604 2/20 0.70
LMNA P02545 1/20 0.70
MAPK1 P28482 1/20 0.70
GPBAR1 Q8TDU6 5/20 0.65
SLC10A2 Q12908 2/20 0.65
TBXA2R P21731 1/20 0.65
PDE3A Q14432 1/20 0.65
NR1H4 Q96RI1 1/20 0.65
CA1 P00915 9/20 0.58
CA2 P00918 9/20 0.58
ABCC4 O15439 1/20 0.58
CYP2C9 P11712 1/20 0.55
HIF1A Q16665 1/20 0.55
VDR P11473 1/20 0.55
CYP3A4 P08684 2/20 0.53
SLCO1B3 Q9NPD5 1/20 0.53
SLCO1B1 Q9Y6L6 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL136045 1.00 MAPT (0.70) MAPTMEN1KMT2AUSP2LMNA
SCHEMBL134379 0.91 GPBAR1 (0.68) MAPTUSP2LMNAMAPK1GPBAR1
SCHEMBL445628 0.91 GPBAR1 (0.68) MAPTUSP2LMNAMAPK1GPBAR1
SCHEMBL134380 0.91 GPBAR1 (0.68) MAPTUSP2LMNAMAPK1GPBAR1
SCHEMBL7893722 0.89 CYP3A4 (0.70) MEN1KMT2AUSP2LMNAGPBAR1
Lagodeoxycholate SCHEMBL5438247 0.83 GPBAR1 (0.79) MAPTMEN1KMT2AUSP2LMNA
Methyl Deoxycholate SCHEMBL21904594 0.83 MAPT (1.00) MAPTMEN1KMT2AUSP2LMNA
Methyl Deoxycholate SCHEMBL21283695 0.83 MAPT (1.00) MAPTMEN1KMT2AUSP2LMNA
Methyl Deoxycholate SCHEMBL21846440 0.83 MAPT (1.00) MAPTMEN1KMT2AUSP2LMNA
Methyl Deoxycholate SCHEMBL16728282 0.83 MAPT (1.00) MAPTMEN1KMT2AUSP2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9598520-B2 Radiation-sensitive resin composition, polymer and method for forming a resist pattern JSR CORPORATION (JP) 2017-03-21 US disclosed
EP-2503392-B1 RADIATION-SENSITIVE RESIN COMPOSITION, POLYMER AND RESIST PATTERN FORMATION METHOD JSR CORP (JP) 2015-04-15 EP disclosed
US-8980529-B2 Radiation-sensitive resin composition, polymer, and resist pattern-forming method JSR CORPORATION (JP) 2015-03-17 US disclosed
US-20130244185-A9 RADIATION-SENSITIVE RESIN COMPOSITION, METHOD FOR FORMING RESIST PATTERN, ORGANIC ACID AND ACID GENERATING AGENT JSR CORPORATION (JP) 2013-09-19 US disclosed
US-8507575-B2 Radiation-sensitive resin composition, polymer, and compound JSR CORPORATION (JP) 2013-08-13 US disclosed
US-20130203000-A1 RADIATION-SENSITIVE RESIN COMPOSITION, POLYMER, AND RESIST PATTERN-FORMING METHOD JSR CORPORATION (JP) 2013-08-08 US disclosed
US-20130065186-A1 RADIATION-SENSITIVE RESIN COMPOSITION, METHOD FOR FORMING RESIST PATTERN, ORGANIC ACID AND ACID GENERATING AGENT JSR CORPORATION (JP) 2013-03-14 US disclosed
US-20120295197-A1 RADIATION-SENSITIVE RESIN COMPOSITION, POLYMER AND METHOD FOR FORMING A RESIST PATTERN JSR CORPORATION (JP) 2012-11-22 US disclosed
EP-2503392-A1 RADIATION-SENSITIVE RESIN COMPOSITION, POLYMER AND RESIST PATTERN FORMATION METHOD JSR Corporation (JP) 2012-09-26 EP disclosed
US-20120065291-A1 RADIATION-SENSITIVE RESIN COMPOSITION, POLYMER, AND COMPOUND JSR CORPORATION (JP) 2012-03-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130244185-A9 RADIATION-SENSITIVE RESIN COMPOSITION, METHOD FOR FORMING RESIST PATTERN, ORGANIC ACID AND ACID GENERATING AGENT GLRA3, RER1, RXRG MAPT 4199/4885MEN1 3808/4885KMT2A 4267/4885
US-20130065186-A1 RADIATION-SENSITIVE RESIN COMPOSITION, METHOD FOR FORMING RESIST PATTERN, ORGANIC ACID AND ACID GENERATING AGENT GLRA3, RER1, FPR3 MAPT 4206/4885MEN1 3872/4885KMT2A 4261/4885
US-20120065291-A1 RADIATION-SENSITIVE RESIN COMPOSITION, POLYMER, AND COMPOUND RAD51, RER1, XRCC5 MAPT 1052/4885MEN1 1479/4885KMT2A 2498/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.