SCHEMBL13439367

SCHEMBL13439367

CC1CCN(c2cc(C3=CCNCC3)ccc2NC(=O)c2ccc(C#N)o2)CC1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ CSF1R P07333 20/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL3964360 0.86 CSF1R (0.76) CSF1R
SCHEMBL13405655 0.86 CSF1R (0.75) CSF1R
SCHEMBL14096401 0.81 CSF1R (1.00) CSF1R
SCHEMBL31157978 0.81 CSF1R (0.81) CSF1R
SCHEMBL13405642 0.81 CSF1R (0.81) CSF1R
SCHEMBL13439323 0.80 CSF1R (1.00) CSF1R
SCHEMBL14096152 0.79 CSF1R (0.73) CSF1R
SCHEMBL13405640 0.76 CSF1R (1.00) CSF1R
SCHEMBL5202289 0.76 CSF1R (1.00) CSF1R
SCHEMBL31157980 0.76 CSF1R (1.00) CSF1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7705042-B2 Class of arylamide compounds useful as inhibitors of c-fms kinase JANSSEN PHARMACEUTICA NV (BE) 2010-04-27 — — US disclosed
EP-1807407-B1 AROMATIC AMIDES AS INHIBITORS OF C-FMS KINASE JANSSEN PHARMACEUTICA NV (BE) 2009-07-29 — — EP disclosed
Send feedback