SCHEMBL14096401

SCHEMBL14096401

CC1CCN(c2cc(-c3ccncc3)ccc2NC(=O)c2ccc(C#N)o2)CC1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ CSF1R P07333 20/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14078173 0.87 CSF1R (0.77) CSF1R
SCHEMBL14096152 0.84 CSF1R (0.73) CSF1R
SCHEMBL13439367 0.81 CSF1R (1.00) CSF1R
SCHEMBL31157980 0.80 CSF1R (1.00) CSF1R
SCHEMBL5202289 0.80 CSF1R (1.00) CSF1R
SCHEMBL13405640 0.80 CSF1R (1.00) CSF1R
SCHEMBL13405642 0.80 CSF1R (0.81) CSF1R
SCHEMBL31157978 0.80 CSF1R (0.81) CSF1R
SCHEMBL14385081 0.80 CSF1R (0.69) CSF1R
SCHEMBL13439323 0.79 CSF1R (1.00) CSF1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7427683-B2 c-fms kinase inhibitors ORTHO-MCNEIL PHARMACEUTICAL, INC. (US) 2008-09-23 — — US disclosed
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